Logistics center is an important node in the logistics network. Scientific layout planning is very important to improve the overall operational efficiency of the logistics center. The layout of each functional area of the logistics center will directly affect the overall planning of the logistics center. The traditional layout method is subjective and cannot objectively reflect the relationship between functional areas. On the basis of combing the relevant literature at home and abroad, this paper makes the layout planning of the functional area of the logistics center. Based on the analysis of the demand of logistics center, the division of functional areas and the determination of the scale of functional areas, the location relationship diagram of functional areas is drawn by using the correlation diagram layout method, so as to obtain the layout scheme of logistics center and provide the basis for the planning of logistics center.