Desmoplastic fibroma in humerus

Apaydin, Melda; Gelal, Fazıl; Avcı, Alper; Adinas, C; Sarsilmaz, Aysegul; Varer, Makbule

doi:10.1111/j.1440-1673.2008.01989.x

Cited by 9 publications

(7 citation statements)

References 5 publications

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“…16,20 Classically, DFs have been described as slow growing and relatively benign. 3,24,28 However, this description is not consistent with the DFs we encountered in our two patients; those tumors caused bony destruction and mediastinal compression leading to hypotension over a relatively short period of time. New genetic studies have shown that DFs have the potential to develop malignant transformation characteristics.…”

contrasting

confidence: 44%

Desmoplastic fibroma of the spine causing severe mediastinal compression and brachial plexus encasement

Lau¹,

Yarlagadda

Jahan³

et al. 2013

SPI

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Desmoplastic fibroma (DF) is a rare bone tumor that accounts for about 0.1%–0.3% of all bone tumors. It is typically characterized as slow growing, but in rare cases it can proliferate extensively and exhibit locally aggressive characteristics. It is found most commonly in the appendicular skeleton and rarely in the axial skeleton. The authors present the cases of 2 women in their 20s with DF originating from the cervicothoracic spine. Both tumors intimately involved the brachial plexus and caused significant impingement of the mediastinum resulting in cardiopulmonary compromise. Both patients underwent hemiclamshell thoracotomies for tumor resection, and in both cases subtotal resection was performed given the encasement of the brachial plexus. Although DF is a benign process, it can be locally aggressive and proliferate at extensive rates. The authors describe these 2 cases, review the literature, and discuss management.

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contrasting

confidence: 44%

Desmoplastic fibroma of the spine causing severe mediastinal compression and brachial plexus encasement

Lau¹,

Yarlagadda

Jahan³

et al. 2013

SPI

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“…Because DFB has dense collagen tissue, the lesion may have a density equal to or higher than surrounding soft tissues with a CT value of 30-66 Hu. High density re ects the dense connective tissue matrix and relative necellularity of tumor 12 . In this group, six patients had the CT value greater than 45 Hu.…”

Section: Discussionmentioning

confidence: 99%

Imaging Diagnosis and Differentiation of Desmoplastic Fibroma of Bone

Zhong

Cao

Guo

et al. 2020

Preprint

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Background: To analyze the imaging features of desmoplastic fibroma of bone (DFB) for correct diagnosis. Methods: The plain radiography, computed tomography (CT) and magnetic resonance imaging (MRI) of 20 patients with DFB were retrospectively analyzed. Results: Twenty patients with DFB were retrieved including eleven males and nine females with an age range of 2-52 years (median 27). The DFB involved the femur in six patients, ilium in five, tibia in four, humerus in two, lumbar vertebra in one, radius in one, and calcaneus in the remaining one. DFB was common in the metaphysis of long bones could involve the diaphysis and epiphysis. The imaging presentations were divided into four types: the cystic expansile destruction, osteolytic destruction, mixed destruction, and paraosseous destruction. CT value was 30 -60 Hu in the lesion area (6 cases CT value＞45Hu). MRI had low mixed signals on T1WI and high mixed signals on T2WI. Soft tissue masses might be present in DFB. Conclusions: DFB is a rare tumor with strong local aggressiveness, imaging presentation of cystic bone destruction, low signals on T1WI and T2WI in the lesion, which are helpful for diagnosis of the disease and differentiation from other ones.

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“…This tumour has been observed infrequently in the diaphysis like the one presented here. Only two previous case reports were there on diaphyseal tumours 3 14. Most patients were younger than 30 years of age 2 10.…”

Section: Discussionmentioning

confidence: 99%

“…A review of literature since the report by Bohm et al , noted an additional 28 patients primarily in the form of case reports 4–13. Known to be a lesion from metaphysis, diaphyseal localisation of the tumour is rarely reported 14. We intend to report an unusual presentation site of this rare tumour successfully treated at our institution.…”

Section: Introductionmentioning

confidence: 94%

Diaphyseal desmoplastic fibroma of humerus - report of a rare presentation

Aggarwal

Gopinathan²,

Dhillon³

et al. 2012

Case Reports

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Desmoplastic fibroma is a rare locally aggressive benign tumour. It is most frequently reported in mandible, metaphysis and metadiaphysis of long bones. This tumour has been observed infrequently in the diaphysis like the one presented here. An 18-year-old female presented with progressive swelling left arm and dull aching pain for 1 year. She had a bony hard lobular well-defined swelling in the midshaft of humerus, which was not warm but tender. There was abnormal mobility present indicating a fracture. Plain radiograph of the affected arm showed an expansile, well-defined, intraosseous, radiolucent lesion with expansion involving the entire circumference of the humerus. An open biopsy was carried out and the report came out to be desmoplastic fibroma. She underwent wide segmental resection and interlocking nailing and bone grafting. After 6 weeks follow-up, the patient had visible callus and by 12 weeks there was significant union.

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Desmoplastic fibroma in humerus

Cited by 9 publications

References 5 publications

Desmoplastic fibroma of the spine causing severe mediastinal compression and brachial plexus encasement

Desmoplastic fibroma of the spine causing severe mediastinal compression and brachial plexus encasement

Imaging Diagnosis and Differentiation of Desmoplastic Fibroma of Bone

Diaphyseal desmoplastic fibroma of humerus - report of a rare presentation

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