Desorption electrospray ionization mass spectrometry imaging (DESI-MSI) in disease diagnosis: an overview

Abstract

Tissue analysis, which is essential to histology and is considered the benchmark for the diagnosis and prognosis of many illnesses, including cancer, is significant. During surgery, the surgical margin of...

Recent developments and applications of ambient mass spectrometry imaging in pharmaceutical research: an overview

“…By assessing and arranging the collected information, it is anticipated that MSI may also evolve into a functional imaging tool to visualize biological events, such as growth, spread, autophagy, iron metabolism, and enzyme catalysis. 193–197…”

Recent Advances and Applications of Ambient Mass Spectrometry Imaging in Cancer Research: An Overview

“…In sharp contrast to the DNA, the metabolome linked to cancer is dynamic and greatly altered by inheritance, dietary habits, and medications. The potential for different results obtained through DESI-MSI investigations 116) on each tumor model encourages more research in this rapidly evolving discipline.…”

Mass spectrometry in the age of green analytical chemistry

“…On the main principles of GAC, ambient MS has achieved a high level of fulfillment, 94 and some ambient MS, namely DESI, has already found an unshakable place in some research areas. 144–146 Current focus on MSI and high-throughput analysis also marks the direction of the development of MS towards GAC. 147,148 Nevertheless, there is no doubt that the development of novel green MS instruments ought to be encouraged and promoted, but not at the expense of the compromised performance and labs’ inordinate financial burden.…”