Detection and differentiation of early acute and following age stages of myocardial infarction with quantitative post-mortem cardiac 1.5 T MR

Schwendener, Nicole; Jackowski, Christian; Persson, Anders; Warntjes, Marcel; Schuster, Frederick L.; Riva, Fabiano; Zech, Wolf-Dieter

doi:10.1016/j.forsciint.2016.10.014

Cited by 25 publications

(27 citation statements)

References 22 publications

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“… 112 In quantitative MRI, correction formulae for relaxation values have been investigated for cadaver temperatures and established in many body tissues and organs. 113 – 116 After correction for temperature, quantitative MRI data can be used to create optimum contrast-weighted images in optimal image planes with better soft tissue discrimination than in CT. The quantitative values can be projected onto a R1-R2-PD space, which may enable measurement of absolute deviation of a specific voxel from normal tissue and automatic detection of pathology (eg, hematoma or infarction) by artificial intelligence.…”

Section: Clinical Applicationsmentioning

confidence: 99%

SyMRI of the Brain

Hagiwara¹,

et al. 2017

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Conventional magnetic resonance images are usually evaluated using the image signal contrast between tissues and not based on their absolute signal intensities. Quantification of tissue parameters, such as relaxation rates and proton density, would provide an absolute scale; however, these methods have mainly been performed in a research setting. The development of rapid quantification, with scan times in the order of 6 minutes for full head coverage, has provided the prerequisites for clinical use. The aim of this review article was to introduce a specific quantification method and synthesis of contrast-weighted images based on the acquired absolute values, and to present automatic segmentation of brain tissues and measurement of myelin based on the quantitative values, along with application of these techniques to various brain diseases. The entire technique is referred to as “SyMRI” in this review. SyMRI has shown promising results in previous studies when used for multiple sclerosis, brain metastases, Sturge-Weber syndrome, idiopathic normal pressure hydrocephalus, meningitis, and postmortem imaging.

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Section: Clinical Applicationsmentioning

confidence: 99%

SyMRI of the Brain

Hagiwara¹,

et al. 2017

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“…PMCT is widely used and accepted as a complementary examination to forensic autopsy in routine forensic examination [3,4]. Over the last 10 years, PMMR has been introduced as an additional tool in post-mortem imaging mainly feasible for diagnosis of soft tissue and organ pathology [5,6]. Acute PTE is a frequently found natural cause of death at autopsy [7].…”

Section: Discussionmentioning

confidence: 99%

Diagnosis of pulmonary infarction in post-mortem computed tomography and post-mortem magnetic resonance imaging—a technical note

et al. 2020

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Pulmonary thromboembolism may be accompanied by pulmonary infarction. Even though pulmonary thromboembolism (PTE) is a frequently found cause of death at autopsy, pulmonary infarction accompanying PTE is a less common finding and may therefore easily be misinterpreted as infectious or cancerous lung disease.Appearance of pulmonary infarction in post-mortem imaging and acquisition parameters helping to identify pulmonary infarctions are not described yet. Based on a case of a 50-year-old man who died due to PTE and presented pulmonary infarction we suggest using a pulmonary algorithm in post-mortem computed tomography combined with post-mortem magnetic resonance imaging of the lungs using conventional T1 and T2 weighted sequences.

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“…[101] It is necessary to perform temperature corrections so the tissue properties of dead tissues approximate those of tissues in living patients before synthetic images are generated. [102][103][104][105]…”

Section: Other Diagnostic Utilitiesmentioning

confidence: 99%

An information theory model for optimizing quantitative magnetic resonance imaging acquisitions

et al. 2020

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I thank my wife, Julika Kaplan, for her constant love and encouragement. She is an inspiration and an unrelenting force of good. I thank my mother, Melanie Mitchell, who has always been first in supporting me through every difficulty and every success in my life. I thank my father, Randall Mitchell. I aspire to be as genuine and kind as he always was. I thank my both of my parents for enabling me to freely pursue my academic interests throughout my life and for encouraging my curiousity always. I thank my brothers, Matthew and Kyle Mitchell. They are true friends. I could not have done this without my family. They have my eternal love and gratitude. v

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Detection and differentiation of early acute and following age stages of myocardial infarction with quantitative post-mortem cardiac 1.5 T MR

Cited by 25 publications

References 22 publications

SyMRI of the Brain

SyMRI of the Brain

Diagnosis of pulmonary infarction in post-mortem computed tomography and post-mortem magnetic resonance imaging—a technical note

An information theory model for optimizing quantitative magnetic resonance imaging acquisitions

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