Atherosclerosis

2011

DOI: 10.1016/j.atherosclerosis.2011.07.005

|View full text |Cite

|

Sign up to set email alerts

|

Detection and quantification of coronary atherosclerotic plaque by 64-slice multidetector CT: A systematic head-to-head comparison with intravascular ultrasound

Stella-Lida Papadopoulou

¹

,

Lisan A. Neefjes

²

,

³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Discussion3

Computed Tomographic Coronary Angiography1

Intravascular Ultrasound (Ivus) Is Invasive and Therefore Not1

Citation Types

Supporting

0

Mentioning

46

Contrasting

0

Year Published

2013

2013

2020

2020

Publication Types

Select...

Article8

Book2

Relationship

Self Cite1

Independent9

Authors

Journals

Cited by 71 publications

(46 citation statements)

References 25 publications

Supporting

0

Mentioning

46

Contrasting

0

Order By: Relevance

“…Coronary computed tomographic (CT) angiography is emerging as a viable approach for the quantification of both calcified and noncalcified plaque (17)(18)(19). The method has been successfully validated for plaque volume in relation to histologic examination and intravascular US (20,21).…”

Section: Discussionmentioning

confidence: 99%

Coronary Artery Plaque Volume and Obesity in Patients with Diabetes: The Factor-64 Study

Kwan¹,

May²,

et al. 2014

View full text Add to dashboard Cite

Purpose:To determine the relationship between coronary plaque detected with coronary computed tomographic (CT) angiography and clinical parameters and cardiovascular risk factors in asymptomatic patients with diabetes. Materials and Methods:All patients signed institutional review board-approved informed consent forms before enrollment. Two hundred twenty-four asymptomatic diabetic patients (121 men; mean patient age, 61.8 years; mean duration of diabetes, 10.4 years) underwent coronary CT angiography. Total coronary artery wall volume in all three vessels was measured by using semiautomated software. The coronary plaque volume index (PVI) was determined by dividing the wall volume by the coronary length. The relationship between the PVI and cardiovascular risk factors was determined with multivariable analysis. Results:The mean PVI (6standard deviation) was 11.2 mm 2 6 2.7. The mean coronary artery calcium (CAC) score (determined with the Agatston method) was 382; 67% of total plaque was noncalcified. The PVI was related to age (standardized b = 0.32, P , .001), male sex (standardized b = 0.36, P , .001), body mass index (BMI) (standardized b = 0.26, P , .001), and duration of diabetes (standardized b = 0.14, P = .03). A greater percentage of soft plaque was present in younger individuals with a shorter disease duration (P = .02). The soft plaque percentage was directly related to BMI (P = .002). Patients with discrepancies between CAC score and PVI rank quartiles had a higher percentage of soft and fibrous plaque (18.7% 6 3.3 vs 17.4% 6 3.5 [P = .008] and 52.2% 6 7.2 vs 47.2% 6 8.8 [P , .0001], respectively). Conclusion:In asymptomatic diabetic patients, BMI was the primary modifiable risk factor that was associated with total and soft coronary plaque as assessed with coronary CT angiography.q RSNA, 2014 Clinical trial registration no. NCT00488033

“…Coronary computed tomographic (CT) angiography is emerging as a viable approach for the quantification of both calcified and noncalcified plaque (17)(18)(19). The method has been successfully validated for plaque volume in relation to histologic examination and intravascular US (20,21).…”

Section: Discussionmentioning

confidence: 99%

Coronary Artery Plaque Volume and Obesity in Patients with Diabetes: The Factor-64 Study

Kwan¹,

May²,

et al. 2014

View full text Add to dashboard Cite

Purpose:To determine the relationship between coronary plaque detected with coronary computed tomographic (CT) angiography and clinical parameters and cardiovascular risk factors in asymptomatic patients with diabetes. Materials and Methods:All patients signed institutional review board-approved informed consent forms before enrollment. Two hundred twenty-four asymptomatic diabetic patients (121 men; mean patient age, 61.8 years; mean duration of diabetes, 10.4 years) underwent coronary CT angiography. Total coronary artery wall volume in all three vessels was measured by using semiautomated software. The coronary plaque volume index (PVI) was determined by dividing the wall volume by the coronary length. The relationship between the PVI and cardiovascular risk factors was determined with multivariable analysis. Results:The mean PVI (6standard deviation) was 11.2 mm 2 6 2.7. The mean coronary artery calcium (CAC) score (determined with the Agatston method) was 382; 67% of total plaque was noncalcified. The PVI was related to age (standardized b = 0.32, P , .001), male sex (standardized b = 0.36, P , .001), body mass index (BMI) (standardized b = 0.26, P , .001), and duration of diabetes (standardized b = 0.14, P = .03). A greater percentage of soft plaque was present in younger individuals with a shorter disease duration (P = .02). The soft plaque percentage was directly related to BMI (P = .002). Patients with discrepancies between CAC score and PVI rank quartiles had a higher percentage of soft and fibrous plaque (18.7% 6 3.3 vs 17.4% 6 3.5 [P = .008] and 52.2% 6 7.2 vs 47.2% 6 8.8 [P , .0001], respectively). Conclusion:In asymptomatic diabetic patients, BMI was the primary modifiable risk factor that was associated with total and soft coronary plaque as assessed with coronary CT angiography.q RSNA, 2014 Clinical trial registration no. NCT00488033

“…Previous studies comparing IVUS and CTA support the feasibility of using the latter to evaluate atherosclerotic plaque size, PB, remodeling, eccentricity, and plaque progression. 14,21,26,27 To ensure the accuracy of the evaluation, we have found that adhering to a standard CTA protocol at baseline and at follow-up is necessary; preferably, the studies …”

Section: Discussionmentioning

confidence: 99%

Quantitative Evaluation of Coronary Plaque Progression by Computed Tomographic Angiography

Liu¹,

Wu²,

Xu³

et al. 2017

Texas Heart Institute Journal

View full text Add to dashboard Cite

C oronary artery disease (CAD), which causes more than 20 million deaths each year, is the world's leading cause of morbidity and death.1,2 Most patients with CAD have many coronary obstructions that are in varying degrees of progression and that pose different risks.3-6 Therefore, understanding the progression of coronary plaque would help physicians make more informed decisions about whether and how to treat patients at risk for CAD.In clinical studies, intravascular ultrasound (IVUS) has traditionally been used to investigate the composition and progression of coronary plaques in the proximal or mid segments of one or 2 major coronary vessels. 7,8 However, it is not appropriate for routine serial evaluations because it carries a small risk of severe procedural complications. In contrast, computed tomographic angiography (CTA) is less expensive and noninvasive. Advances in computed tomographic (CT) technology and post-imageprocessing techniques have made it possible not only to detect stenosis with coronary CTA, but also to use it to quantitatively analyze coronary plaques. [9][10][11][12][13] In recent years, a few serial studies with CTA have appeared in the literature, 14-17 but most of them have focused on lesions in diseased segments of the coronary tree. Our objective in this study was to use CTA to examine the natural history of coronary atherosclerosis along the full length of the right coronary artery (RCA) tree and to investigate serial changes in the minimum luminal area (MLA), plaque burden (PB), plaque volume (PV), and arterial remodeling. Patients and MethodsTwenty-one patients treated at Beijing Anzhen Hospital from 2010 through 2013 were studied retrospectively (Table I). Inclusion criteria were as follows: age >18 years, availability of 2 coronary CTA scans taken >6 months apart, and diagnosis of acute coronary syndrome (ACS) during the initial physical examination. Exclusion criteria included previous percutaneous coronary intervention (PCI) to the RCA or coronary artery bypass grafting, severe valvular heart disease, irregular heart rhythm, renal fail-

“…39,40 It has been also hypothesized that noninvasive imaging modalities such as CCTA further stratify intermediate risk patients to a very high risk group. 41,42 Moreover, in IVUS and MSCT comparative studies, 24,43,44 CCTA was been shown to accurately evaluate atherosclerotic plaque size, remodeling, eccentricity, and plaque composition. Based on the small mean differences between CCTA and IVUS with virtual histology measurements, it was suggested that quantitative CCTA analysis could be acceptably used on a population level.…”

Section: Discussionmentioning

confidence: 99%

Rationale and design of the Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography IMaging (PARADIGM) registry: A comprehensive exploration of plaque progression and its impact on clinical outcomes from a multicenter serial coronary computed tomographic angiography study

¹

,

²

,

³

et al. 2016

American Heart Journal

View full text Add to dashboard Cite

BACKGROUND:The natural history of coronary artery disease (CAD) in patients with

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Product

Browser Extension Assistant by scite Citation Statement Search Reference Check Visualizations Dashboards Explore Journals Explore Organizations Explore Funders Embedding Badge Embedding Citation Search Pricing

Resources

Blog Help & FAQ Accessibility Statement API Terms For Universities & Governments For Researchers For Publishers For Corporate, Pharma & Enterprise Author Marketing Become an Affiliate Get an organization trial or quote scite Data & Services

About

News & Press Careers Read our Paper Coverage

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Copyright © 2024 scite LLC. All rights reserved.

Made with 💙 for researchers

Part of the Research Solutions Family.