Détection et traitement précoce des sujets à haut risque clinique de psychose : définitions et recommandations

Michel, Chantal; Toffel, Elodie; Schmidt, Stefanie; Eliez, Stéphan; Armando, Marco; Solida-Tozzi, Alessandra; Schultze‐Lutter, Frauke; Debbané, Martin

doi:10.1016/j.encep.2017.01.005

Cited by 12 publications

(2 citation statements)

References 14 publications

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“…Strauss et al, 2010). Therefore, psychosocial intervention in the early stages that stimulates social functioning, and indirectly, contributes to clinical and functional recovery, must be guaranteed (Michel et al, 2017; Schmidt et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

Survival of patients with severe mental disorders: Influence of social functioning

Vázquez-Reyes

Martín-Rodríguez

Pérez-San-Gregorio

et al. 2023

Int J Soc Psychiatry

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Background: Patients with severe mental disorders have a high risk of premature death due to the interaction of various factors. Social functioning is a strategic functional factor in understanding the course of psychotic disorders. Aim: Analyze the relationship between social functioning and its various dimensions and survival during a 10-year follow-up. Method: The Social Functioning Scale (SFS) was administered to 163 close relatives of patients under treatment at a Community Mental Health Unit. Survival was described by Kaplan–Meier analysis and any differences in survival by level of social functioning were found by long-rank analysis. Finally, Cox regression was used to predict premature mortality. Results: Significant differences in mortality were identified in the interpersonal behavior dimension of social functioning, while there were no significant gender or diagnostic differences in the rest of the dimensions. The interpersonal behavior dimension and age were found to be factors predicting premature death. Conclusion: These findings show the protective effect of social functioning retained by patients with psychotic disorders on their survival, and the need to apply evidence-based psychotherapy focused on recovery of social functioning in the early stages of the disorder.

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Section: Discussionmentioning

confidence: 99%

Survival of patients with severe mental disorders: Influence of social functioning

Vázquez-Reyes

Martín-Rodríguez

Pérez-San-Gregorio

et al. 2023

Int J Soc Psychiatry

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“…Yet, conversion rates seem to have generally declined in CHR-P samples in recent years ( 13 ). At present, the alternative assessment of the two symptomatic UHR criteria based on attenuated and transient psychotic symptoms and COGDIS have been recommended for clinical use ( 9 , 14 ) to support the timely application of indicated treatments to attenuate the risk for conversion to clinical psychosis ( 15 , 16 ). Importantly however, beyond the risk of clinical psychosis, CHR-P patients who do not transition to psychotic disorders have been repeatedly reported to have adverse mental health and functional outcomes, including poor social functioning, persistence or development of non-psychotic mental health disorders, and non-remission of CHR-P symptoms ( 17 ).…”

Section: Introductionmentioning

confidence: 99%

The role of mentalizing in the relationship between schizotypal personality traits and state signs of psychosis risk captured by cognitive and perceptive basic symptoms

Salaminios,

Sprüngli-Toffel,

Michel

et al. 2023

Front. Psychiatry

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ObjectiveSchizotypal traits and disturbances in mentalizing (the capacity to understand the mental states driving one’s own and others’ behaviors) have been implicated in increased vulnerability for psychosis. Therefore, we explored the associations linking schizotypal traits, mentalizing difficulties and their interactions to clinical high-risk for psychosis (CHR-P), as captured by the Basic Symptoms (BS) approach, during adolescence and young adulthood.MethodsEighty-seven adolescents and young adults from the general population (46% male, 44% female; age: 14–23 years) were assessed with the Schizophrenia Proneness Interview (SPI-CY/A) for 11 perceptive and cognitive BS, with the Schizotypal Personality Questionnaire (SPQ) for schizotypal traits, and with the Reflective Functioning Questionnaire (RFQ) for self-reported mentalizing abilities. The RFQ evaluates the level of certainty (RFQc scale) and uncertainty (RFQu scale) with which individuals use mental state information to explain their own and others’ behaviors.ResultsLogistic regression models showed significant positive effects of the SPQ disorganization scale on perceptive BS and of the SPQ interpersonal scale on cognitive BS. Post-hoc analyses revealed that schizotypal features pertaining to odd speech and social anxiety, respectively, were associated with perceptive and cognitive BS. Furthermore, higher scores on the RFQu scale and lower scores on the RFQc scale independently explained the presence of cognitive BS. Finally, significant interaction effects between RFQc and SPQ odd speech on perceptive BS, and between RFQc and SPQ social anxiety on cognitive BS were found.ConclusionOur findings suggest that schizotypal traits and mentalizing significantly relate both independently and through their interactions to the presence of cognitive and perceptive BS included in CHR-P criteria. Furthermore, mentalizing dysfunction may contribute in the relation between schizotypal traits and early state signs of CHR-P. Mentalizing may support both detection and early treatment of CHR-P among adolescents and young adults who present with trait risk for psychosis.

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Clinical Evaluation and Intervention of Emerging Psychosis: A Mentalization-Informed Perspective

Debbané

Salaminios

Weijers

et al. 2022

Psychosis and Personality Disorders

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Détection et traitement précoce des sujets à haut risque clinique de psychose : définitions et recommandations

Cited by 12 publications

References 14 publications

Survival of patients with severe mental disorders: Influence of social functioning

Survival of patients with severe mental disorders: Influence of social functioning

The role of mentalizing in the relationship between schizotypal personality traits and state signs of psychosis risk captured by cognitive and perceptive basic symptoms

Clinical Evaluation and Intervention of Emerging Psychosis: A Mentalization-Informed Perspective

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