Detection of Explosives in a Dynamic Marine Environment Using a Moored TNT Immunosensor

Charles, Paul T.; Adams, André A.; Deschamps, Jeffrey R.; Veitch, Scott P.; Hanson, Al; Kusterbeck, Anne W.

doi:10.3390/s140304074

Cited by 20 publications

(11 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To our knowledge, the present study is the only one that has employed passive sampling to detect munitions constituents released from a controlled source in an aquatic environment. Demonstration of an immunosensor installed on a field‐deployable platform for continuous sampling of TNT over a period of 18 h has been reported (Charles et al ). The sensor was calibrated to detect concentrations ranging from 1 to 100 μg/L, well above the range of detection for POCIS in the present study.…”

Section: Resultsmentioning

confidence: 99%

Field validation of POCIS for monitoring at underwater munitions sites

Rosen

Lotufo

George

et al. 2018

Enviro Toxic and Chemistry

View full text Add to dashboard Cite

The present study evaluated polar organic chemical integrative samplers (POCIS) for quantification of conventional munitions constituents, including trinitrotoluene (TNT), aminodinitrotoluenes, diaminonitrotoluenes, dinitrotoluene, and hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) in a field setting. The POCIS were deployed at varying distances from the commonly used explosive formulation composition B (39.5% TNT, 59.5% RDX, 1% wax) in an embayment of Santa Rosa Sound (Pensacola, FL, USA). Time-weighted averaged water concentrations from a 13-d deployment ranged from 9 to 103 ng/L for TNT and RDX, respectively, approximately 0.3 to 2 m from the source. Concentrations decreased with increasing distance from the source to below quantitation limits (5-7 ng/L) at stations greater than 2 m away. Moderate biofouling of POCIS membranes after 13 d led to a subsequent effort to quantify potential effects of biofouling on the sampling rate for munitions constituents. After biofouling was allowed to occur for periods of 0, 7, 14, or 28 d at the field site, POCIS were transferred to aquaria spiked with munitions constituents. No significant differences in uptake of TNT or RDX were observed across a gradient of biofouling presence, although the mass of fouling organisms on the membranes was statistically greater for the 28-d field exposure. The present study verified the high sensitivity and integrative nature of POCIS for relevant munitions constituents potentially present in aquatic environments, indicating that application at underwater military munitions sites may be useful for ecological risk assessment. Environ Toxicol Chem 2018;37:2257-2267. Published 2018 Wiley Periodicals Inc. on behalf of SETAC. This article is a US government work and, as such, is in the public domain in the United States of America.

show abstract

Section: Resultsmentioning

confidence: 99%

Field validation of POCIS for monitoring at underwater munitions sites

Rosen

Lotufo

George

et al. 2018

Enviro Toxic and Chemistry

View full text Add to dashboard Cite

show abstract

“…Nitrocellulose industry wastewater is highly toxic to the environment because it contains chlorophenols, chlorolignins, organic acids, acid resins, and dioxins [23,32], as well as high levels of organic matter and metal ions [22]. There are few studies analyzing the toxicity of nitrocellulose to aquatic organisms [37-39], but many studies reported the detrimental effects of other explosives, such as 2,4,6-trinitrotoluene (TNT), 1,3,5-Trinitroperhydro-1,3,5-triazine (RDX), and 1,3,5,7tetranitro-1,3,5,7-tetrazocane (HMX) [40][41][42][43][44][45][46].…”

Section: Cbmentioning

confidence: 99%

Intensification of the leachate treatment process of nitrocellulose production

Santos¹,

Siqueira²,

Silva³

et al. 2020

IJAERS

View full text Add to dashboard Cite

show abstract

“…In addition to faster medical diagnostics [ 22 , 23 , 24 , 25 ], microfluidics is being applied in drugs of abuse testing [ 26 , 27 , 28 , 29 ], pollutant detection [ 30 , 31 , 32 , 33 , 34 ], combatting biowarfare [ 35 , 36 , 37 , 38 ] and also in laboratory routines in a research context, as described below.…”

Section: Microfluidics—from Small Benchtop Biosensors To High-thromentioning

confidence: 99%

Microfluidic Organ/Body-on-a-Chip Devices at the Convergence of Biology and Microengineering

Perestrelo

Águas

Rainer

et al. 2015

Sensors

134

View full text Add to dashboard Cite

Recent advances in biomedical technologies are mostly related to the convergence of biology with microengineering. For instance, microfluidic devices are now commonly found in most research centers, clinics and hospitals, contributing to more accurate studies and therapies as powerful tools for drug delivery, monitoring of specific analytes, and medical diagnostics. Most remarkably, integration of cellularized constructs within microengineered platforms has enabled the recapitulation of the physiological and pathological conditions of complex tissues and organs. The so-called “organ-on-a-chip” technology, which represents a new avenue in the field of advanced in vitro models, with the potential to revolutionize current approaches to drug screening and toxicology studies. This review aims to highlight recent advances of microfluidic-based devices towards a body-on-a-chip concept, exploring their technology and broad applications in the biomedical field.

show abstract

Detection of Explosives in a Dynamic Marine Environment Using a Moored TNT Immunosensor

Cited by 20 publications

References 18 publications

Field validation of POCIS for monitoring at underwater munitions sites

Field validation of POCIS for monitoring at underwater munitions sites

Intensification of the leachate treatment process of nitrocellulose production

Microfluidic Organ/Body-on-a-Chip Devices at the Convergence of Biology and Microengineering

Contact Info

Product

Resources

About