Detection of Fe&lt;inf&gt;3&lt;/inf&gt;O&lt;inf&gt;4&lt;/inf&gt; Magnetic Nanoparticles using Giant Magnetoresistance (GMR) Sensor Based on Multilayer and Spin Valve Thin Films by Wheatstone Bridge Circuit

Nurpriyanti, Indah; Pardede, Indra; Suharyadi, Edi; Kato, Takeshi; Iwata, S.

doi:10.1109/issimm.2016.7803717

Cited by 8 publications

(10 citation statements)

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“…The addition of PEG can decrease the agglomeration and reduce the particle size. In addition, ring diffraction patterns for both of them, are closely related to XRD analysis, which corresponding to the crystal plane (220), (311), (400), (440), and (511) [8,10].…”

Section: Resultsmentioning

confidence: 83%

“…The typical real-time binding curves (Change of output voltage vs. external magnetic field) for magnetic streptavidin with different concentrations (10,20,30, and 40 l/ml) on the GMR sensors in Wheatstone bridge are shown in Fig. 2a.…”

Section: Resultsmentioning

confidence: 99%

“…The Fe 3 O 4 magnetic nanoparticles were synthesized by chemical co-precipitation method [8,10]. Room temperature VSM measurements have been conducted by using Riken Denshi Co Ltd vibrating sample magnetometer (VSM).…”

Section: Experiments Detailsmentioning

confidence: 99%

“…Transmission electron microscopy (TEM) analysis was performed using a JEOL JEM-1400. The streptavidin magnetic particles (Sigma-Aldrich) were dispersed in ethanol by sonication for 5 min and vortexed for 15 s. Four different concentrations (10,20,30, and 40 l/ml) were prepared. Fe 3 O 4 /PEG was synthesized following a simple two steps co-precipitation approach with polyetthylene glycole 4000 (PEG-4000) with concentration ratio of 0.…”

Section: Experiments Detailsmentioning

confidence: 99%

“…Even though a unique resistance can be used as sensing element, a Wheatstone bridge setup is always a good recommendation as the starting step in the design of resistive sensors [9]. Thus, Nurpriyanti et al investigated the detection of Fe 3 O 4 magnetic nanoparticles using GMR sensors based on Co/Cu multilayer by Wheatstone bridge circuit to provide output signal of voltage [10]. However, this sensor was not portable and real-time.…”

Section: Introductionmentioning

confidence: 99%

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Wheatstone bridge-giant magnetoresistance (GMR) sensors based on Co/Cu multilayers for bio-detection applications

Antarnusa

Swastika

Suharyadi

2018

J. Phys.: Conf. Ser.

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Abstract.A Wheatstone bridge-giant magnetoresistance (GMR) sensor was successfully developed for a potential biomaterial detection. In order to achieve this, a giant magnetoresistive [Co(1.5nm/Cu(1.0nm)] 20 multilayer structures have been fabricated by DC magnetron sputtering method, showing a magnetoresistance (MR) of 2.7%. The X-Ray diffraction (XRD) patterns showed that Co/Cu film multilayer has a high degree of crystallinity with a single peak corresponding to face-centered cubic (111) structure at 2 = 44.1 . Co/Cu multilayers exhibit a soft magnetic behavior with the saturation magnetization (Ms) of 1489 emu/cc and the coercivity (Hc) of 11.2 Oe. The magnetite Fe 3 O 4 nanoparticles used as a bimolecular labels (nanotags) were synthesized via co-precipitation method, exhibiting a soft magnetic behavior with Ms of 77.16 emu/g and Hc of 49 Oe. XRD patterns and transmission electron microscopy (TEM) images showed that Fe 3 O 4 was well crystallized and it grew in their inverse spinel structure with an average size of around 10 nm. The GMR sensor design was used to detect a biomolecules of streptavidin magnetic particles with concentration 10, 20, 30, and 40 l/ml and -amylase enzyme with consentration 10, 20, 30, and 40 l/ml captured using polyethylene glycol (PEG)/ Fe 3 O 4 nanoparticles. Various applied magnetic fields of 0-650 Gauss have been performed using electromagnetic with the various currents of 0-5 A. Here, the final value of the output voltage signals for the streptavidin magnetic particles concentration is 1.2 mV (10 l/ml). The output voltage changes with the increase of concentration. It was reported that the output voltage signal of the Wheatstone bridge exhibits log-linear function in real time measurement of the concentration of streptavidin magnetic particles and -amylase enzyme respectively, making the sensor suitable for use as a biomolecule concentration detector. Thus, the combination of Co/Cu multilayer, Wheatstone bridge, magnetite and PEG polymer has potential application to be used in bio-detection applications where ultra-small bio-labels are needed.

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Section: Resultsmentioning

confidence: 83%

Section: Resultsmentioning

confidence: 99%

Section: Experiments Detailsmentioning

confidence: 99%

Section: Experiments Detailsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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