Detection of prostatic peripheral zone cancer based on quantitative analysis of 3.0T MR Diffusion Tensor Imaging

Abstract

In this study, we aim to evaluate the diagnostic performance of diffusion tensor imaging (DTI) in detecting prostatic peripheral zone cancer and to deduce its clinical utility. The area under curve (AUC) of the receiver operating characteristic (ROC) curves was used to evaluate the diagnostic efficiency of ADC value, FA value and their combination. The diagnostic threshold values of ADC and FA were also determined. It was concluded that DTI quantitative indexes has moderately high diagnostic accuracy in detecting prostate cancer , while the ADC value had higher diagnostic efficiency than the FA value.