Detection of quantitative trait loci for growth and fatness in pigs

Abstract

International audienceA quantitative trait locus (QTL) analysis of growth and fatness data from a three-generation experimental cross between Meishan (MS) and Large White (LW) pig breeds is presented. Six boars and 23 F1 sows, the progeny of six LW boars and six MS sows, produced 530 F2 males and 573 F2 females. Nine growth traits, i.e. body weight at birth and at 3, 10, 13, 17 and 22 weeks of age, average daily gain from birth to 3 weeks, from 3 to 10 weeks and from 10 to 22 weeks of age, as well as backfat thickness at 13, 17 and 22 weeks of age and at 40 and 60 kg live weight were analysed. Animals were typed for a total of 137 markers covering the entire porcine genome. Analyses were performed using two interval mapping methods: a line-cross (LC) regression method where founder lines were assumed to be fixed for different QTL alleles and a half-/full-sib (HFS) maximum likelihood method where allele substitution effects were estimated within each half-/full-sib family. Both methods revealed highly significant gene effects for growth on chromosomes 1, 4 and 7 and for backfat thickness on chromosomes 1, 4, 5, 7 and X, and significant gene effects on chromosome 6 for growth and backfat thickness. Suggestive QTLs were also revealed by both methods on chromosomes 2 and 3 for growth and 2 for backfat thickness. Significant gene effects were detected for growth on chromosomes 11, 13, 14, 16 and 18 and for backfat thickness on chromosome 8, 10, 13 and 14. LW alleles were associated with high growth rate and low backfat thickness, except for those of chromosome 7 and to a lesser extent early-growth alleles on chromosomes 1 and 2 and backfat thickness alleles on chromosome 6

Naturalised Vitis Rootstocks in Europe and Consequences to Native Wild Grapevine

“…This may explain the high genetic diversity indices shown by our results and by other European studies [26], [28]. Interestingly, rootstocks show even higher diversity indices even though they are nearly restricted to alluvial zones.…”

The genomic mosaicism of hybrid speciation

“…A modified version of the CRIMAP 2.4 software ( 66 ), including added utilities provided by X. Liu and M. Grosz (Monsanto, St. Louis, MO), was used for the map construction. Initially, SNPs were assigned to linkage groups (LGs) on the basis of pairwise linkages and the grouping algorithm implemented in the AUTOGROUP option of the program.…”

A Whole Genome Association Study on Meat Quality Traits Using High Density SNP Chips in a Cross between Korean Native Pig and Landrace

“…European domestic breeds, or Meishan vs. western breeds were extensively used in QTL studies (Andersson et al, 1994; Rothschild et al, 1995, 2007; Janss et al, 1997; Bidanel and Rothschild, 2002; Hu et al, 2007). After the first report on genome-wide scan and detection of QTL for growth, length of small intestine, and fat deposition in pig (Andersson et al, 1994), many QTL studies using F 2 cross populations were performed on growth and fat deposition (Knott et al, 1998; Paszek et al, 1999; Rohrer, 2000; Wada et al, 2000; Bidanel et al, 2001; Malek et al, 2001a; Kim et al, 2005), carcass traits (Andersson-Eklund et al, 1998; Rohrer et al, 1998), and meat quality (de Koning et al, 1999, 2001; Malek et al, 2001b). Recently, several QTL studies on purebreds for meat quality were also reported (Uemoto et al, 2008; Soma et al, 2011).…”