Detection of visual field defects in pre-perimetric glaucoma using fundus-oriented small-target perimetry

Nakatani, Yusuke; Ohkubo, Shinji; Higashide, Tomomi; Iwase, Aiko; Kani, Kazutaka; Sugiyama, Kazuhisa

doi:10.1007/s10384-012-0133-8

Cited by 4 publications

(2 citation statements)

References 20 publications

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“…Some studies have suggested that these eyes have glaucomatous optic disc abnormalities with localized RNFL damage in the fundus picture but without abnormal VF results. 16 However, this definition is highly subjective and dependent on examiner experience. Thus, Jampel et al 17 found that the interobserver agreement among glaucoma specialists in judging progressive optic disc changes from stereophotographs was slight to fair.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of RETICs Glaucoma Diagnostic Calculators in Preperimetric Glaucoma

Moreno-Montañés

García-Nieva

osio

et al. 2018

Trans. Vis. Sci. Tech.

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PurposeTo evaluate two glaucoma diagnostic calculators (GDC) in a group of eyes with preperimetric glaucoma (PPG).MethodsAll eyes (n = 265) included in this study had ocular hypertension with normal visual fields (VFs) on repeated VF tests. PPG was defined as progression in the Guided Progression Analysis software from Cirrus-optical coherence tomography (GPA-OCT). Three PPG types were defined according to the GPA-OCT software as follows: (1) GPA-OCT with one or more red boxes in two or more columns; (2) GPA-OCT with two or more red boxes in two or more columns; and (3) GPA-OCT with two or more red boxes in two or more columns (definition 2), and in the last scan one or more red box in the RNFL average or quadrants. Nonparametric tests, areas under the receiver operating characteristic curve (AUC), and Bland-Altman tests were assessed.ResultsDefinitions one, two, and three were met by 44 (16.6%), 29 (10.9%), and 11 (4.2%) eyes, respectively. The GDC indices (means ± standard deviations) were, respectively, 14.49 ± 21.55% and 26.06 ± 22.50% using the combined and quantitative GDC (P < 0.001) in all eyes. Both GDC showed higher glaucoma probability in the PPG group (P < 0.04; combined GDC AUCs, 0.720–0.833; quantitative GDC AUCs, 0.700–0.839). GDC values were higher (P < 0.01) with greater GPA progression.ConclusionsThe values of both GDC were higher in the PPG group than the ocular hypertension group. The GDC were higher when more columns in the GPA software indicated progression. Both GDC showed a similar ability to detect PPG.Translational RelevanceThese calculators facilitate diagnosis of PPG in ocular hypertensive eyes.

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Section: Discussionmentioning

confidence: 99%

Evaluation of RETICs Glaucoma Diagnostic Calculators in Preperimetric Glaucoma

Moreno-Montañés

García-Nieva

osio

et al. 2018

Trans. Vis. Sci. Tech.

View full text Add to dashboard Cite

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“…14,17,18 It was recognized that the long test duration of SAPRO was a major limitation of this procedure, where 236 presentations were required to examine a 158 field with a 3.28 grid. 14 More recently, scotoma-oriented perimetry (SCOPE) 5,11 and fundus-oriented perimetry (FOP) 4,16,19,20 have been reported, which involve a clinician selecting more points to test within a region of interest. A procedure that automatically adds a fixed number of locations for further testing to a completed 24-2 pattern by computing the gradient between previously tested locations has also been proposed recently (Aoyama K, et al IOVS 2013;54:ARVO Abstract 3914).…”

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confidence: 99%