Detection rate of serrated polyps and serrated polyposis syndrome in colorectal cancer screening cohorts: a European overview

Abstract

The detection rate of SPs is variable among screening cohorts, and standards for reporting, detection and histopathological assessment should be established. The median rate, as found in this study, may contribute to define uniform minimum standards for males and females between 50 and 75 years of age.

Serrated polyposis syndrome may go undiagnosed even in structured colorectal cancer screening programmes performed by endoscopists with otherwise good quality indices

“…In our cohort, SPs were detected less frequently than in the primary colonoscopy screening cohort from the Netherlands and Poland,1 and we also observed a marked difference in SP detection rates between endoscopists which might have led to missed diagnosis of SPS. However, detection rates for proximal SPs and large SPs were comparable to the Polish cohort 1.…”

“…However, detection rates for proximal SPs and large SPs were comparable to the Polish cohort 1. It has been demonstrated that SPS is frequently unrecognised even in patients with large colorectal SPs which has been attributed to a failure in detecting SPs and not systematically applying WHO criteria 7…”

“…We have read the article by Ijspeert et al with great interest as it comprises the largest series of colonoscopies concerning the serrated polyposis syndrome (SPS) published so far 1. SPS is characterised by multiple serrated polyps (SP) throughout the colon and it is associated with an increased risk of colorectal cancer (CRC) 2.…”

Prevalence of serrated polyposis syndrome in an FIT-based colorectal cancer screening cohort in Italy

“…A guaiac faecal occult blood test cohort from the UK showed a frequency of SPS ranging from 0.03% to 0.66% 1 2. Other cohorts based on primary colonoscopy showed a prevalence of SPS between 0.1% and 0.4% 1.…”

“…We read with interest the recent data reported by IJspeert et al ,1 Biswas et al 2 and Moreira et al 3 whom evaluated the prevalence of serrated polyposis syndrome (SPS), a disease characterised by the development of multiple serrated polyps throughout the colon with an increased risk to develop colorectal cancer (CRC),4 inside CRC screening programmes. A guaiac faecal occult blood test cohort from the UK showed a frequency of SPS ranging from 0.03% to 0.66% 1 2.…”