Determination of aliphatic amines using N-succinimidyl benzoate as a new derivatization reagent in gas chromatography combined with solid-phase microextraction

Zhao, Yuanyuan; Cai, Ling; Jing, Zhaoxia; Wang, Hong; Yu, Jing; Zhang, Hua‐Shan

doi:10.1016/j.chroma.2003.09.025

Cited by 59 publications

(13 citation statements)

References 36 publications

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“…In fact, prolonged reaction times coupled with elevated temperatures could cause hydrolysis of the imine derivatives in the alkaline solution; on the contrary, PFBAY is quite stable in water, even under alkaline conditions. The obtained results also demonstrated that even in cases where the derivatization reaction is performed on the fiber, Although this analysis time is comparable or slightly higher with respect to other derivatization SPME protocols [2,14,[25][26][27], it has the advantage of avoiding the addition of the derivatization agent to each sample which, can potentially constitute an additional source of error in the analysis routine. On the other hand, other extraction techniques such as vortex assisted liquidliquid microextraction [28], micro extraction in packed syringe (MEPS) [29], single drop microextraction (SDME) [30], air-assisted liquid-liquid microextraction (AALLME) [9], in syringe derivatization [6] used for determination of derivatized amines often lack automation options, employ organic solvents and include tedious procedures.…”

Section: Optimization Of Reaction Conditions In Aqueous Phasementioning

confidence: 62%

“…Amines can also be derivatized by a fast reaction with chloroformates under mild reaction conditions to yield carbamate derivatives [8,9]. The use of N-succinimidyl benzoate (SNB) for derivatization of short chain aliphatic primary amines, with formation of amides as derivatization products, was also reported [10]. Lastly, base-Schiff formation can be performed with a variety of reagents in aqueous solutions at room temperature, however, pentafluorobenzaldehyde (PFBAY) is the most commonly used derivatization reagent of this class [11].…”

Section: Introductionmentioning

confidence: 98%

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A facile and fully automated on-fiber derivatization protocol for direct analysis of short-chain aliphatic amines using a matrix compatible solid-phase microextraction coating

Gionfriddo

Passarini

Pawliszyn

2016

Journal of Chromatography A

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Solid-phase microextraction (SPME) analysis of short-chain aliphatic amines (C3-C6) in aqueous solutions was investigated using pentafluorobenzaldehyde (PFBAY) as on-fiber derivatization reagent. A standard gas generating vial agent was used for on-fiber loading of the derivatization agent so as to avoid the need for its regeneration at each derivatization cycle. Several parameters such as loading time, reaction temperature, and reaction/extraction time were optimized for headspace and direct sampling in aqueous solutions. Three different coating chemistries were tested and their performances compared in order to achieve the best compromise between sensitivity and analysis throughput. The newly developed PDMS/DVB/PDMS coating showed superior performance in terms of extraction efficiency while the capability to prevent on-fiber degradation of the derivatizing products. The optimized method was used for quantitation of short-chain aliphatic amines in aqueous samples and provided detection limits in the low ppb range for all the amines tested with accuracy values between 79 and 120%. The method was applied towards the analysis of environmental water samples and the accuracy of the results was evaluated by different calibration approaches.

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Section: Optimization Of Reaction Conditions In Aqueous Phasementioning

confidence: 62%

Section: Introductionmentioning

confidence: 98%

A facile and fully automated on-fiber derivatization protocol for direct analysis of short-chain aliphatic amines using a matrix compatible solid-phase microextraction coating

Gionfriddo

Passarini

Pawliszyn

2016

Journal of Chromatography A

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“…HS-SPME technique is widely used for extracting various kinds of chemicals. Among them, in-vial (in situ) derivatization is frequently used for haloacetic acids (HAAs) [21,23] and acetic acid [67], aldehyde compounds [25,124,165], phenoxy acid herbicides [68], phenolic pollutants [17,18,82,91,159], aliphatic amines [120,125], acaricide fenbutatin oxide (FBTO) [131], acetone [111], selective serotonin reuptake inhibitors (SSRIs) such as venlafaxine, fluvoxamine, fluoxetine, citalopram, and sertraline [97], and organometallic compounds such as organotin [29,31,86,87,127,128,138,139,160], organolead [31,86,89,160], and organomercury [31,128,129,140,160]. On-fiber in situ derivatization is used for analyzing chemicals such as aldehyde compounds [27,105,164], carbonyls compounds [28], and thiol compounds [171].…”

Section: Watermentioning

confidence: 99%

Application of Solid-Phase Microextraction Combined with Derivatization for Polar Compound Sampling in Environmental Analysis

Yang¹,

Luan²

2016

Solid Phase Microextraction

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Solid-phase microextraction (SPME) is a solvent-free sample preparation technique using a fused-silica fiber coated with an appropriate stationary phase. Derivatization is often necessary to determine substances with poor chromatographic behavior, high reactivity, and/or volatility or thermal instability. SPME derivatization technique can be operated under different combined modes and may be influenced by factors such as sample matrix, SPME, derivatization, and desorption condition. Combined with derivatization, HS-SPME, DI-SPME, membrane-protected SPME, and in-tube SPME have been applied to the analysis of a vast amount of chemicals, i.e., aldehydes and acetone, amines, organic acids, phenolic compounds, pesticide, metal and organic metal species, and pharmaceutical and personal care products (PPCPs) in a wide range of environmental matrices, including air, water, soil, and sediment samples. This chapter reviews the mode and method development of the derivatization technique, the derivatization reagents, and reaction mechanism, as well as its applications in environmental analysis.

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“…HPLC another tool frequently used is slightly laborious and expensive, as it requires stringent purifications of samples and large amounts of solvents and washings of column. These methods often require derivatization of the amine (Zhao et al 2003;Hao et al 2004).…”

Section: Introductionmentioning

confidence: 99%

Spectrophotometric method for estimation of aliphatic primary amines in biological samples

Varma

Gaikwad

2007

World J Microbiol Biotechnol

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A method based on Rimini test for aliphatic amines was studied and developed for quantitative estimation of aliphatic primary amines. The method involves action of the amine with acetone to form schiff base which complexes with sodium nitroprusside to give violet colour. The absorption maximum in the visible range of the spectrum, for the reaction mixture was found to be 550 nm. The pH (8-11) and reaction time scan for the assay were optimized. A linear relation of concentration (0.2-3 mg/mL) of amine against absorbance at 550 nm was established. Interference due to other reaction components was negligible (±0.02 mg/mL) as compared to the sample in buffer. 1, 3-dimethyl butylamine was used as the model amine and the method was applied to other amines; it was observed that when electron-withdrawing substituents are present in the molecule the reaction is retarded, as the incubation time was longer. This method is useful for estimation of aliphatic primary amine in biological samples.

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Determination of aliphatic amines using N-succinimidyl benzoate as a new derivatization reagent in gas chromatography combined with solid-phase microextraction

Cited by 59 publications

References 36 publications

A facile and fully automated on-fiber derivatization protocol for direct analysis of short-chain aliphatic amines using a matrix compatible solid-phase microextraction coating

A facile and fully automated on-fiber derivatization protocol for direct analysis of short-chain aliphatic amines using a matrix compatible solid-phase microextraction coating

Application of Solid-Phase Microextraction Combined with Derivatization for Polar Compound Sampling in Environmental Analysis

Spectrophotometric method for estimation of aliphatic primary amines in biological samples

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