Determination of Antibacterial Activity of St. John's Wort (Hypericum perforatum L.) Oil, Nigella Sativa Oil, Clove (Eugenia caryophyllata) Oil, Orange Peel (Citrus sinensis) and Garlic (Allium sativa) Oil Against Microorganisms Isolated From Clinical Samples

Çelebi, Özgür; BAŞER>, Sümeyye; Güler, Mustafa Can; Çelebi, Demet; Çelebi, Şaban

doi:10.56766/ntms.1177132

New Trends in Medicine Sciences

2023

DOI: 10.56766/ntms.1177132

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Determination of Antibacterial Activity of St. John's Wort (Hypericum perforatum L.) Oil, Nigella Sativa Oil, Clove (Eugenia caryophyllata) Oil, Orange Peel (Citrus sinensis) and Garlic (Allium sativa) Oil Against Microorganisms Isolated From Clinical Samples

Özgür Çelebi

Sümeyye BAŞER>

Mustafa Can Güler

et al.

Abstract: Objective: The aim of this study is to detect St. John's Wort, Nigella sativa, Clove, Orange Peel and Garlic oil on bacteria isolated from blood culture to determine its antibacterial effect. Methods: One hundered blood samples sent to … Medical Microbiology Laboratory between 1 June 2021 and 1 January 2022 were analyzed with blood culture system. Bacteria isolated from blood culture were passaged into blood agar. Bacterial suspension was prepared from the bacterial colonies at 0.5 Mc Farland turbidity. … Show more

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Cited by 2 publications

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Preparation of Centella asiatica (L). and Hypericum perforatum (St. John's Wort) Plant Extracts and Development of Anti-Aging Herbal Cream Formulations

AYDINLI,

DEMİR,

GÖKSU

2023

International Journal of Traditional and Complementary Medicine Research

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Objective: The aim of the study is to use two different plant extracts such as St. John's Wort (Hypericum perforatum) and Centella asiatica (L.) in the cream formulation and to determine the anti-aging effect of the new formulation. Material-Method: The plants used in the study were obtained commercially and plant extracts were obtained using the classical extraction techniques in the literature. The active ingredients in the obtained extracts were determined by HPLC method. Physical, protective efficacy, microbial analysis and anti-aging tests were carried out for cream formulations obtained with extracts. Results: Plant extraction studies were carried out in the study. Centella asiatica (L.) was extracted with 20.8% yield at 20 mL of methanol and 60 ℃. As a result of HPLC analysis, it was determined that there were 1740 mg/kg asiatic acid and 4380 mg/kg madecasic acid in the extract. In the extraction studies performed on Hypericum perforatum, the expected active ingredient, hypericin, was not found. For this reason, commercial extract containing 2.5% hyperforin was obtained and the studies were continued on these extracts and final cream formulations were obtained. Conclusion: pH, viscosity, density, protective effectiveness tests and microbial analysis tests of the final formulations were performed. In addition, in vitro anti-aging studies have been carried out in accredited laboratories. With in-vitro anti-aging tests, it was determined that the level of collagen 1A increased more in the formulation where both extracts were used together.

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Preparation of Centella asiatica (L). and Hypericum perforatum (St. John's Wort) Plant Extracts and Development of Anti-Aging Herbal Cream Formulations

AYDINLI,

DEMİR,

GÖKSU

2023

International Journal of Traditional and Complementary Medicine Research

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The antimicrobial activity of Hypericum perforatum L. flower extract against food pathogens and its non-enzymatic antioxidant activity

Guler,

Okmen

2024

Kragujevac J Science

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Foodborne pathogens pose a significant hazard to food safety. Most cases of foodborne illnesses are caused by bacterial pathogens that have infiltrated the food chain at some point, from farm to kitchen. According to the World Health Organization (WHO), approximately one-third of individuals in developed countries are affected by foodborne pathogens each year. Although there are studies on Hypericum perforatum L. in the literature, research in Turkey remains limited. Therefore, the aim is to contribute to the literature by studying H. perforatum samples from the Yaraş region of Muğla province in Turkey. This study specifically aims to investigate the antimicrobial activities against foodborne pathogens and the antioxidant activity of H. perforatum in Muğla. The in vitro antimicrobial activities of flower components from plants grown in Mugla were evaluated using the disc diffusion method and broth dilution test. Additionally, the extracts underwent ABTS (2,2'-azinobis-(3-ethyl benzothiazoline-6-sulfonic acid)) free-radical testing to evaluate their antioxidant activity. The extract exhibited a maximum inhibition zone of 16 mm against Staphylococcus aureus and Listeria monocytogenes. Notably, S. aureus and L. monocytogenes demonstrated the lowest sensitivity to H. perforatum methanol extract (1625 µg/mL). The methanol extract displayed moderate antioxidant activity, with a 53% ABTS radical scavenging capacity. Consequently, the extracts of H. perforatum exhibited both antimicrobial and antioxidant potential.

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Determination of Antibacterial Activity of St. John's Wort (Hypericum perforatum L.) Oil, Nigella Sativa Oil, Clove (Eugenia caryophyllata) Oil, Orange Peel (Citrus sinensis) and Garlic (Allium sativa) Oil Against Microorganisms Isolated From Clinical Samples

Cited by 2 publications

References 28 publications

Preparation of Centella asiatica (L). and Hypericum perforatum (St. John's Wort) Plant Extracts and Development of Anti-Aging Herbal Cream Formulations

Preparation of Centella asiatica (L). and Hypericum perforatum (St. John's Wort) Plant Extracts and Development of Anti-Aging Herbal Cream Formulations

The antimicrobial activity of Hypericum perforatum L. flower extract against food pathogens and its non-enzymatic antioxidant activity

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