Determination of O2 using colour sensing from image processing with mobile devices

López-Ruiz, Nuria; Martínez-Olmos, Antonio; Vargas-Sansalvador, Isabel M. Pérez de; Fernández-Ramos, M.D.; Carvajal, M.; Capitán-Vallvey, L.F.; Palma, A.

doi:10.1016/j.snb.2012.06.007

Cited by 48 publications

(38 citation statements)

References 35 publications

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“…[2][3][4][5][6][7][8][9][10][11][12][13][14][15] Ozcan and co-workers and Henry and co-workers have recently reviewed the literature in the field. [17][18][19] Test strips, however, typically only provide semi-quantitative results; for full quantitation, test kits for liquid samples remain the gold standard.…”

Section: Introductionmentioning

confidence: 99%

Broadly Available Imaging Devices Enable High-Quality Low-Cost Photometry

et al. 2015

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This paper demonstrates that, for applications in resource-limited environments, expensive microplate spectrophotometers-which are used in many central laboratories for parallel measurement of absorbance of samples-can be replaced by photometers based on inexpensive and ubiquitous, consumer electronic devices (e.g., scanners and cell-phone cameras). Two devices-i) a flatbed scanner operating in transmittance mode and ii) a camera-based photometer constructed from a cell phone camera, a planar light source, and a cardboard box-demonstrate the concept. These devices illuminate samples in microtiter plates from one side, and use the RGB-based imaging sensors of the scanner/camera to measure the light transmitted to the other side. The broadband absorbance of samples (RGB-resolved absorbance) can be calculated using the RGB color values of only three pixels per micro-well. Rigorous theoretical analysis establishes a well-defined relationship between the absorbance spectrum of a sample and its corresponding RGB-resolved absorbance. The linearity and precision of measurements performed with these low-cost photometers on different dyes that absorb across the range of the visible spectrum, and chromogenic products of assays (e.g., enzymatic, ELISA) demonstrates that these low-cost photometers can be used reliably in a broad range of chemical and biochemical analyses. The ability to perform accurate measurements of absorbance on liquid samples, in parallel and at low cost, would enable testing, typically reserved for well-equipped clinics and laboratories, to be performed in circumstances where resources and expertise are limited.

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Section: Introductionmentioning

confidence: 99%

Broadly Available Imaging Devices Enable High-Quality Low-Cost Photometry

et al. 2015

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“…In 1995, Vinogradov et al found several Pd-chelated porphyrins which showed high sensitivity to oxygen concentration changes [48]. Subsequently, numerous formulations of phosphorescent probes have been developed involving copolymers [49], nanoparticles [50–52], dendrimers [53–55], and hydrogels [13, 56]. …”

Section: Applications Of Metalloporphyrinsmentioning

confidence: 99%

Emerging applications of porphyrins in photomedicine

et al. 2015

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Biomedical applications of porphyrins and related molecules have been extensively pursued in the context of photodynamic therapy. Recent advances in nanoscale engineering have opened the door for new ways that porphyrins stand to potentially benefit human health. Metalloporphyrins are inherently suitable for many types of medical imaging and therapy. Traditional nanocarriers such as liposomes, dendrimers and silica nanoparticles have been explored for photosensitizer delivery. Concurrently, entirely new classes of porphyrin nanostructures are being developed, such as smart materials that are activated by specific biochemicals encountered at disease sites. Techniques have been developed that improve treatments by combining biomaterials with photosensitizers and functional moieties such as peptides, DNA and antibodies. Compared to simpler structures, these more complex and functional designs can potentially decrease side effects and lead to safer and more efficient phototherapies. This review examines recent research on porphyrin-derived materials in multimodal imaging, drug delivery, bio-sensing, phototherapy and probe design, demonstrating their bright future for biomedical applications.

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“…Small analytes and molecules have also been detected using cellphone platforms as valuable analytic measurement tools [96][97][98][99]. …”

Section: Sensing Of Small Analytes and Moleculesmentioning

confidence: 99%