Determination of the Diffusivity and Location and Pressure Dependent Permeability of Porcine Coronary Arteries

Abstract

The modeling of drug delivery into tissues utilizes coupled convective and diffusive transport and therefore requires the experimental determination of the governing constants used in these models [1, 2]. The use of minimally destructive methods to determine these properties ensures increased accuracy [3]. Having the ability to test for strain or intraluminal pressure dependence also provides improved accuracy to the definitions of these properties.