Developing a New Generic Health and Wellbeing Measure: Psychometric Survey Results for the EQ-HWB

Peasgood, Tessa; Mukuria, Clara; Brazier, John; Marten, Ole; Kreimeier, Simone; Luo, Nan; Mulhern, Brendan; Greiner, Wolfgang; Pickard, A. Simon; Augustovski, Federico; Engel, Lidia; Gibbons, Luz; Yang, Zhihao; Monteiro, A; Kuharic, Maja; Belizán, María; Bjørner, Jakob Bue

doi:10.1016/j.jval.2021.11.1361

Cited by 44 publications

(32 citation statements)

References 27 publications

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“…50% of respondents in the ceiling were flagged as potentially problematic, using a threshold established by the international teams in other analyses. 17 At the instrument level, 15% was adopted as a threshold to signal potential problems. 32 EQ-5D-5L ceiling effects were further examined using the distribution of EQ-HWB-S responses for those who reported full health on the EQ-5D-5L (no problems on all dimensions, health state 11111).…”

Section: Discussionmentioning

confidence: 99%

“…26 More information on the survey design and implementation can be found elsewhere. 17 EQ-HWB item pool and EQ-HWB-S descriptive system…”

Section: Survey Questions and Instrumentsmentioning

confidence: 99%

“…The psychometric testing efforts narrowed down the item pool, producing a 25-item profile measure (EQ-HWB) and a 9-item classifier amenable to valuation (EQ-HWB-S). 17 Because this analysis used data collected during the stage of psychometric assessment and item reduction phase, there are slight differences between the wording of the items used in this analysis and the next-stage EQ-HWB-S experimental version. The correspondence between the items used here and the final EQ-HWB-S is presented in Table 1.…”

Section: Survey Questions and Instrumentsmentioning

confidence: 99%

“…The first 4 stages of the E-QALY project culminated in the development of a 25-item profile measure, the EQ-HWB, and a 9-items classifier, the EQ-HWB-S, which could be valued and disseminated on stages 5 and 6. 14,16,17 The EQ-5D items were considered alongside the pool of EQ-HWB candidate items in the psychometric assessment stage of the E-QALY project, and their performance was not inferior to the remaining item pool. Nevertheless, head-to-head comparisons showed that the EQ-5D items were outperformed by the items chosen to integrate the final version of the EQ-HWB-S health classifier.…”

Section: Introductionmentioning

confidence: 99%

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A Comparison of a Preliminary Version of the EQ-HWB Short and the 5-Level Version EQ-5D

2022

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Section: Discussionmentioning

confidence: 99%

“…26 More information on the survey design and implementation can be found elsewhere. 17 EQ-HWB item pool and EQ-HWB-S descriptive system…”

Section: Survey Questions and Instrumentsmentioning

confidence: 99%

Section: Survey Questions and Instrumentsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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A Comparison of a Preliminary Version of the EQ-HWB Short and the 5-Level Version EQ-5D

2022

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“…Empirical studies had found inconsistent conceptualization of health domains, insufficient internal consistency, and unsatisfactory item-to-scale correlation when these instruments were used among the Chinese respondents [ 10 , 14 , 15 ]. In the development of new EuroQoL Health and Wellbeing instrument (EQ-HWB) that aims to assess the impact on the health and well-being of care recipients and caregivers [ 16 ], the conceptual model was reasonably well confirmed in the UK, Australia, and the USA, but not in China [ 17 , 18 ]. Moreover, most of the existing generic PBMs were developed decades ago.…”

Section: Introductionmentioning

confidence: 99%

China Health Related Outcomes Measures (CHROME): Development of a New Generic Preference-Based Measure for the Chinese Population

Chen

et al. 2022

PharmacoEconomics

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Background and Objectives Existing generic preference-based measures were all developed in Western countries. Evidence shows that the Chinese population may have different perceptions about health and health-related quality of life. This study aimed at developing a descriptive system of a new generic preference-based measure under the initiative of China Health Related Outcomes Measures (CHROME). Methods Qualitative data were collected through semi-structured interviews conducted in-person or online. Respondents were recruited from both the general public and populations with chronic diseases. Open-ended questions about the respondent’s perception of general health and important aspects of health-related quality of life were asked. Probing questions based on a systematic review of existing generic preference-based measures were also used. The framework analysis was used to synthesize the qualitative data. Candidate items for the descriptive system were selected following the ISPOR and COSMIN guidelines. Expert panel review and cognitive debriefings were conducted for further revisions. Results Qualitative interviews were conducted among 68 respondents, with 48.5% male and a mean age of 47.8 years (range 18–81 years). In total, 1558 codes were identified and then aggregated to 31 sub-themes and corresponding six themes to inform the development of the initial version of the descriptive system. Feedback from the expert panel survey and meeting ( n = 15) and the cognitive debriefing interviews ( n = 30) was incorporated into the revised version of the measure. Finally, the generic version of CHROME (CHROME-G) included 12 items across six domains, namely, pain, fatigue, appetite, mobility, vision, hearing, sleeping, daily activities, depression, worry, memory, and social interactions. The descriptive system used a mix of four-level and five-level response options and a 7-day recall period. Conclusions The CHROME-G is the first generic preference-based measure to be developed based on the inputs from the Chinese populations. Supplementary Information The online version contains supplementary material available at 10.1007/s40273-022-01151-9.

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Comparing EQ-5D-3L and EQ-5D-5L in measuring the HRQoL burden of 4 health conditions in China

et al. 2022

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Developing a New Generic Health and Wellbeing Measure: Psychometric Survey Results for the EQ-HWB

Cited by 44 publications

References 27 publications

A Comparison of a Preliminary Version of the EQ-HWB Short and the 5-Level Version EQ-5D

A Comparison of a Preliminary Version of the EQ-HWB Short and the 5-Level Version EQ-5D

China Health Related Outcomes Measures (CHROME): Development of a New Generic Preference-Based Measure for the Chinese Population

Comparing EQ-5D-3L and EQ-5D-5L in measuring the HRQoL burden of 4 health conditions in China

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