Developing metal-mediated and catalyzed reactions in air and water

Catalytic properties of carboxylic acid functionalized-polymer microsphere-stabilized gold metallic colloids

“…Water is an interesting reaction medium in the context of green chemistry and catalysis in various monoand biphasic systems [28].…”

A Mechanochemical Zinc-Mediated Barbier-Type Allylation Reaction under Ball-Milling Conditions

“…1 Since the seminal publication by Barbier in 1899, 2 the use of a variety of metals has been reported, such as, zinc, 3a magnesium, 3b samarium, 3c aluminium, 3d indium, 3e cadmium, 3f antimony, 3g lead, 3h tin, 3i bismuth 3j and manganese 3k as well as asymmetric processes 4 and even aqueous media variants. 5 Perhaps the most studied Barbier-type reaction is the allylation of carbonyl groups to deliver versatile homoallylic alcohol products. 1 A common feature of these processes is the requirement of a base metal, whose physical form, solubility and oxide surface layer can lead to variable outcomes.…”

Halocyclization of Olefinic 1,3-Dicarbonyls and Olefinic Amides in Aqueous Media Open in Air at Room Temperature

“…Without question, water, with its properties of low cost, safety, nontoxicity, and eco-friendliness, appears to be an attractive reaction medium in green and sustainable chemistry. − Moreover, dimethyl sulfoxide (DMSO) as a universal green solvent, similar to water, provides a wider space for the development of green organic reaction processes. − On the other hand, realizing organic reactions simply open to the air at room temperature is one of the most ideal methodologies as it can minimize cost and energy consumption, as well as increase stability and security. − Taking all the above into consideration, the implementation of organic transformation in the water/DMSO mixed media under an air atmosphere at room temperature conditions is a fascinating yet challenging target for synthetic chemists.…”