Development a spectrofluorometric micellar supported encapsulated method for micro determination of silver ion using new 2,6-disubstituted pyridine derivatives

Sayqal, Ali; Ahmed, Saleh A.; Hussein, Essam M.; Kassem, Mohammed A.

doi:10.1016/j.saa.2020.118711

Cited by 9 publications

(4 citation statements)

References 51 publications

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“…The values for electronegativity ( χ ), chemical potential ( μ ), global hardness ( η ), global electrophilicity index ( ω ), global softness ( S ), and absolute softness ( S ) were calculated by using several equations in which the results are represented in Table 1. [ 40,41 ] The most significant parameter that indicates the relative toxicity and reactivity of various selected sites is electrophilicity ( ω ). Electrophilicity may signify energy stability and may characterize the activity of the suggested Schiff base.…”

Section: Resultsmentioning

confidence: 99%

“…The values for electronegativity ( χ ), chemical potential ( μ ), global hardness ( η ), global electrophilicity index ( ω ), global softness ( S ), and absolute softness ( S ) were calculated, and the results obtained were given in Table 1. [ 40,41 ] The completely optimized geometries of the [Fe(L)]Cl 3 , [Co(L)]Cl 2 , [Ni(L)]Cl 2 , and [Cu(L)]Cl 2 complexes were illustrated in Figure S6. For Fe(III) complexes, the selected values for bond lengths and bond angles showed an octahedral geometry around the Fe(III) ion (Table S5).…”

Section: Resultsmentioning

confidence: 99%

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Structural characterization, spectroscopic studies, and molecular docking studies on metal complexes of new hexadentate cyclic peptide ligand

Moustafa

Sabry

Zayed

et al. 2021

Applied Organom Chemis

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New cyclic peptide ligand (L), 4,7,17,20‐tetrabenzyl‐2,5,8,16,19,22‐hexaoxo‐3,6,9,15,18,21‐hexaaza‐1(1,3)‐benzenacyclodocosaphane‐10‐carboxylic acid (BOABCA), was prepared using the recommended method. The ligand (L) and its complexes have been proven by using elemental analyses, molar conductivity, and magnetic moment measurements. The structural properties of the title compounds were explored using spectroscopy (1H NMR, ultraviolet [UV]–visible, and Fourier transform infrared [FT‐IR]) and mass spectrometry. The thermal decomposition of the ligand and its complexes are measured by thermal analysis (thermogravimetry [TG] and derivative thermogravimetry [DTG]) technique. The ligand (L) acts as neutral hexadentate with NNOOOO coordination sites and coordinating to the metal ions via the two nitrogen and four oxygen atoms. Bond lengths, bond angles, and quantum chemical characteristics have been established for the ligand and its complexes. The scanning electron microscope (SEM) analysis confirmed the presence of Fe(III) and Ni(II) complexes in nanostructure. The structural formula for the examined cyclic peptide ligand was optimized using Gaussian09 program. The energy gaps and other relevant theoretical parameters were computed applying the DFT/B3LYP technique. Antibacterial properties of the BOABCA ligand (L) and its transition metal complexes have been evaluated. In vitro biological properties for BOABCA ligand (L) and its transition metal complexes were carried out against Gram(+) bacteria (Bacillis subtilis and Staphylococcus aureus) and Gram(−) bacteria (Escherichia coli and Pseudomonas aeruginosa) employing agar diffusion method. The results showed that title compounds are biologically active than the parent BOABCA ligand. Molecular docking has shown favorable interaction between the title compounds and crystal structure of 3t88‐E. coli, 3ty7‐S. aureus, 5h67‐B. subtilis, and 5i39‐P. aeruginosa receptors.

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Section: Resultsmentioning

confidence: 99%

“…The values for electronegativity ( χ ), chemical potential ( μ ), global hardness ( η ), global electrophilicity index ( ω ), global softness ( S ), and absolute softness ( S ) were calculated, and the results obtained were given in Table 1. [ 40,41 ] The completely optimized geometries of the [Fe(L)]Cl 3 , [Co(L)]Cl 2 , [Ni(L)]Cl 2 , and [Cu(L)]Cl 2 complexes were illustrated in Figure S6. For Fe(III) complexes, the selected values for bond lengths and bond angles showed an octahedral geometry around the Fe(III) ion (Table S5).…”

Section: Resultsmentioning

confidence: 99%

Structural characterization, spectroscopic studies, and molecular docking studies on metal complexes of new hexadentate cyclic peptide ligand

Moustafa

Sabry

Zayed

et al. 2021

Applied Organom Chemis

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“…Besides complex formation these derivatives also serve as sensors for Ag ion in various environmental samples. [103] Mononuclear Ag complexes based on coordinated py derivatives are also in field for various biological applications. Complexes based on readily available ligands, 183 and 184) were tested for their antimicrobial efficacy and the activity was compared with AgSD (Silver sulfadiazine).…”

Section: Coordination Compounds For Biological Applicationsmentioning

confidence: 99%

Pyridine Derivatives as Biologically Active Precursors; Organics and Selected Coordination Complexes

Khan

2021

ChemistrySelect

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Pyridine (py) is an important heterocyclic compound and is an integral part of various natural products. There are various medicines containing py ring system being available in the market to combat different human ailments. Observing the medicine market, Omeprazole, a widely used py-based drug in medicinal market since 1998. Netupitant (an antiemitic drug, since 2014) is used in combination with another drug to prevent acute and delayed vomiting and nausea associated with cancer chemotherapy led the run towards development of anticancer drugs. Several drugs have been approved by FDA for the treatment of cancer in recent years such as, Abemaciclib (2015), Lorlatinib (2018), Apalutamide (2018) and Ivosidenib (2019). Research on py on the bases of these advancements is an evergreen field and associated with greater hopes to address several disease related issues. Several compounds are in the process of clinical trials and are expected to serve various purposes in days to come. This review article deals with recent findings in py chemistry and its coordination complexes. The medicinal efficiency has been argued for organic and inorganic derivatives. Selected biological applications are hereby discussed as follow up study of our report in 2015. Suitable literature prior to 2015 has also been incorporated in appropriate places in order to cover the scope in broader sense.

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“…In addition, several Saudi cultivars were metabolically characterized to evaluate their nutritional value (Hamad et al, 2015). Sayqal et al (2020) utilized crystal-based mid-infrared spectroscopy for fingerprinting study to distinguish between Saudi dates fruits for food adulteration. Likewise, nine KSA varieties were studied based on their phytochemical characteristics, physical properties, and biological activities (Abdul-Hamid et al, 2020).…”

Section: Introduction Introduction Introduction Introductionmentioning

confidence: 99%

Characterization of palm date varieties (Phoenix dactylifera L.) growing in Saudi Arabia: Phenotypic diversity estimated by fruit and seed traits

ALRASHIDI

JAMAL

ALAM

et al. 2023

Not Bot Horti Agrobo

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In order to determine the variation and the degree of diversity among the most well-known Saudi date palm (Phoenix dactylifera L.), this study applied various widely detectible fruit and seed features. The properties of the fruit and seeds were described using ten phenotypic traits. Eighteen date palm varieties from six production sites were used in this study (Ḥaʼil, Al-Madina, Al-Hassa, Al-Qassim, Kharaj, Najran). The data was analysed by Pearson r correlation. The principal components analysis (PCA) and UPGMA clustering were used to analyse the data set. According to PCA, the results showed significant variation among the analysed varieties. Our data shows that seed ratio varies among all varieties. The mean seed weight ratio varies between 4 and 13%. Varieties ‘Raziz’, ‘Lubab’ and ‘Wasily’ demonstrate higher seed ratio (over 10%). Whereas, Fankha depicts a 5 and 4% fresh and dry seed ratio. The statistical analysis indicates that the seed ratio in all 18 varieties is comparable in fresh and dry fruits. The result suggests variation among the numerous features due to dissimilarities and heterogeneity. However, the obtained results also propose the clustering and grouping of closely related features, e.g., weights of fresh and dry fruits. Eventually, it is suggested to conduct additional research on Saudi date palms utilizing more phenotypic traits in order to have a better understanding of the pack of morphological descriptors.

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Development a spectrofluorometric micellar supported encapsulated method for micro determination of silver ion using new 2,6-disubstituted pyridine derivatives

Cited by 9 publications

References 51 publications

Structural characterization, spectroscopic studies, and molecular docking studies on metal complexes of new hexadentate cyclic peptide ligand

Structural characterization, spectroscopic studies, and molecular docking studies on metal complexes of new hexadentate cyclic peptide ligand

Pyridine Derivatives as Biologically Active Precursors; Organics and Selected Coordination Complexes

Characterization of palm date varieties (Phoenix dactylifera L.) growing in Saudi Arabia: Phenotypic diversity estimated by fruit and seed traits

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