Development and characterization of chitosan/polyvinyl alcohol polymer material with elastolytic and collagenolytic activities

Декіна, С. С.; Romanovska, I. I.; Sevastyanov, O. V.; Shesterenko, Ye.A.; Ryjak, Alexandra; Varbanets, L.D.; Natalia, Dzubluk; Muratov, Eugene

doi:10.1016/j.enzmictec.2019.109399

Cited by 10 publications

(3 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Moreover, Dekina et al studied PVA/CS films containing Bacillus thuringiensis var. israelensis which were found to be promising wound dressing materials given that the films revealed collagenolytic and elastolytic activities [152] .…”

Section: Biomaterials For Wound Managementmentioning

confidence: 99%

Recent trends on wound management: New therapeutic choices based on polymeric carriers

Okur

Karantas

Şenyiğit

et al. 2020

Asian Journal of Pharmaceutical Sciences

225

115

View full text Add to dashboard Cite

Wound healing is an unmet therapeutic challenge among medical society since wound assessment and management is a complex procedure including several factors playing major role in healing process. Wounds can mainly be categorized as acute or chronic. It is well referred that the acute wound displays normal wound physiology while healing, in most cases, is seemed to progress through the normal phases of wound healing. On the other hand, a chronic wound is physiologically impaired. The main problem in wound management is that the majority of wounds are colonized with microbes, whereas this does not mean that all wounds will be infected. In this review, we address the problems that clinicians face to manage while treat acute and chronic wounds. Moreover, we demonstrate the pathophysiology, etiology, prognosis and microbiology of wounds. We further introduce the state of art in pharmaceutical technology field as part of wound management aiming to assist health professionals to overcome the current implications on wound assessment. In addition, authors review researches which included the use of gels and dermal films as wound healing agents. It can be said that natural and synthetic drugs or carriers provide promising solutions in order to meet the wound management standards. However, are the current strategies as desirable as medical society wish?

show abstract

Section: Biomaterials For Wound Managementmentioning

confidence: 99%

Recent trends on wound management: New therapeutic choices based on polymeric carriers

Okur

Karantas

Şenyiğit

et al. 2020

Asian Journal of Pharmaceutical Sciences

225

115

View full text Add to dashboard Cite

show abstract

“…Однак безпосередньо носії мають погані плівкоутворювальні властивості та низьку пластичність. Тому як матриці для створення біоактивних полімерних матеріалів перспективним є використання їх суміші з ПВС [18][19][20][21].…”

Section: іммобілізовані форми серратіопептидази: біохімічні та фізико-хімічні властивостіunclassified

New polymeric materials of complex proteolytic action

Romanovska¹,

Rizhak²,

Dekina³

et al. 2021

New Functional Substances and Materials for Chemical Engineering

View full text Add to dashboard Cite

“…Fungal biomass cultivation can undergo using two main approaches, solid-state (SSF) and submerged substrate (SMF) fermentation utilizing agricultural and/or food industrial wastes and by-products as alternatives for expensive fermentation media to minimize chitosan production costs as it could be considered a green synthesis economic approach [11]. Owing to the multi-dimensional, and high functionality structure of chitosan it has widespread application in food, paper, wastewater treatment, pharmaceutical, biomedical, agricultural, biotechnological, and food-related industries [8,14]. Utilizing chitosan as a biological coating to improve the shelf life of meat products can be considered a healthy method of meat preservation [15,16].…”

Section: Introductionmentioning

confidence: 99%

Chitosan production from agro-wastes by Aspergillus tubingensis: A sustainable approach for beef burger quality improvement

Amin,

Abou-Taleb,

Abd-Elhalim

et al. 2024

Preprint

View full text Add to dashboard Cite

Background Chitosan is commonly obtained by deacetylation of chitin from crustacean shell wastes such as shrimp and crab, but unfortunately, these sources appear limited for their unavailability. So, an alternative abundant chitin source is in need as fungi mycelia. Results In this study, chitosan production through submerged (SMF) and solid-state fermentation (SSF) of Aspergillus tubingensis utilizing various agro-wastes and by-products like whey, blackstrap molasses, beet waste, rice (husk& straw), wheat bran and sawdust as a sole carbon source was investigated. The best waste was beet waste (33.12% and 38.61% of chitin and chitosan yields for SSF and whey (whey (24.22% and 35.90% of chitin and chitosan yields) for SmF, as compared to the control of sucrose (17.11% and 20.38% of chitin and chitosan yields) after 8–12 and 8 days of incubation, respectively. The fungal polymer had antibacterial activity against Staphylococcus aureus DSMZ20231,Salmonella Typhimurium ATCC14028,Bacillus cereus DSMZ345, Pseudomonas fluorescens NRRL800, and Escherichia coli ATCC69373 at a significant concentration of 1.0% were assayed using Kirby-Bauer disc diffusion method. Staph. aureus DSMZ20231& S. Typhimurium ATCC14028 were more susceptible to chitosan, which gave the largest zone inhibition of 47 and 43 mm, respectively. Moreover, the polymer's antibacterial activity was tested in the broth medium during different incubation periods (12-48h). results indicated that all tested pathogenic strains exhibited complete inhibition after 24 h incubation except B. cereus DSMZ345 was the most stable up to 48h. Application of fungal chitosan (1.0%) for a laboratory-manufactured beef burger led to improve quality analysis of the texture, physical or technological and chemical properties than control without chitosan. At the same time, beef burger supplemented with chitosan was significantly accepted overall by the panelist than the control. Therefore, fungal chitosan extended the beef burger's shelf life and maintained its quality indices during freezing storage. Conclusions Fungal chitosan is a beneficial natural antimicrobial, and applying it to beef burgers improves microbiological, technological, and chemical quality while also extending shelf life by up to 8 weeks, making it a viable alternative to chemical protective additives. Future research on this fungal chitosan will focus on large-scale meat or poultry preservation or additive applications.

show abstract

Development and characterization of chitosan/polyvinyl alcohol polymer material with elastolytic and collagenolytic activities

Cited by 10 publications

References 27 publications

Recent trends on wound management: New therapeutic choices based on polymeric carriers

Recent trends on wound management: New therapeutic choices based on polymeric carriers

New polymeric materials of complex proteolytic action

Chitosan production from agro-wastes by Aspergillus tubingensis: A sustainable approach for beef burger quality improvement

Contact Info

Product

Resources

About