Development and characterization of hydrogels based on natural polysaccharides: Policaju and chitosan

Abstract

The development of hydrogels based on natural polysaccharides was investigated by preparing mixtures of policaju/chitosan at weight ratios of 1:4 and 2:3. Utilizing dynamic light scattering (DLS) techniques for these mixtures, an increase on the hydrodynamic particle radius was observed varying their pH from 3.0 to 12.0. Furthermore, a reduction of ζ-potential was also observed for the same pH interval. Following rounds of drying/hydration cycles at a specific pH value, hydrogel matrices were formed. The pore size distribution of these formed hydrogels was examined using scanning electron microscopy. Further FT-IR analyses confirmed a physical interaction between the polysaccharides policaju and chitosan. Swelling experiments revealed water uptake values, after 24h of immersion in water, close to 270% for 1:4, and 320% for 2:3 hydrogels. Finally, rheological measurements were then conducted in order to confirm hydrogel viscoelastic features. These results indicate a promising road to biomaterials fabrication and biomedical applications.

Evaluation of the application of cashew gum as an excipient to produce tablets

“…Cashew gum has been studied by various researchers in a wide range of fields, including the pharmaceutical sector. In this respect, this substance has been investigated for the formation of hydrogels, tablet fillers, mucoadhesive propertis, micro and nanoparticles for controlled drug release [5][6][7][8] .…”

Preparation and characterization of vanillin-crosslinked chitosan therapeutic bioactive microcarriers

“…The bands at 910 and 1162 cm −1 correspond to saccharine structure. The absorption peaks at 1629, 1595 and 1327 cm −1 are characteristic of CS for the amide I, II and III, respectively [32]. The broad band around 1082 cm −1 indicates the C O stretching vibration of CH 2 OH in CS.…”

Cashew Tree Gum: A Scientific and Technological Review

“…The gum may be associated with other polymers giving good filmogenic features which provide new industrial applications for the same. Table 2 below presents a list of published works associating cashew gum with other polymers such as Acrylamide [25], Alginate [26,27], Carboxymethylcellulose [28], Cassava starch and Carnaubawaxe [29], Chitosan [30,31,32,33,34]; Metallicphthalocyanines, polyallylamine, hydrochloride [35]. Studies of cashew rubber blends with polyvinyl alcohol (PVA) have presented several applications in the formulation of films.…”