Abstract:Circulating tumor cells (CTCs) are shed from primary or metastatic tumors into the peripheral blood circulation which carry a wealth of information for cancer diagnosis, treatment and prognosis. However, most of current CTCs isolation and detection methods provide only cancer cell counting information which is far from meeting clinical needs. In addition to the numbers of CTCs, the target proteins and gene mutations carried by CTCs can also be used for clinical diagnosis, disease monitoring and therapeutic sel… Show more
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