Development and Evaluation of a Virtual Reality Puzzle Game to Decrease Food Intake: Randomized Controlled Trial

Abstract

Background Virtual reality (VR) has gained popularity in daily life, and VR food cues seem to elicit food cravings, similar to real food cues. However, little is known about the impact of VR food cues on actual food intake. Objective In real life (RL), exposure to food cues in a situation in which the desire to eat food interferes with the completion of a food-related task reduces the subsequent food intake (ie, the pre-exposure effect). In this study, we examine, on the one hand, whether the pre-exposure effect could be replicated in RL and, on the other hand, whether this effect could be extended to VR contexts. Methods The study used a 2 (stimulus type: food vs nonfood) × 2 (mode: VR vs RL) between-subject design (n=175). Participants were randomly assigned to 1 of the 4 conditions. Results We found the main effect of mode on food intake, with a higher food intake after both VR conditions than after RL conditions (P=.02). In addition, among female participants, we found that exposure to both food cues (ie, VR and RL) resulted in lower food intake than exposure to both nonfood cues (P=.05). In contrast, this effect was not observed among male participants (P=.34). Additionally, VR and RL cues generated similar emotional and behavioral responses (eg, arousal and game difficulty). Conclusions We were unable to replicate the exposure effect in our complete sample. Subgroup analyses, however, showed that for women, exposure to food cues (either in VR or in RL) reduces food intake, indicating that a VR pre-exposure procedure may effectively be applied exclusively for women. Trial Registration ClinicalTrials.gov NCT05169996; https://clinicaltrials.gov/ct2/show/NCT05169996

Virtual reality in the diagnostic and therapy for mental disorders: A systematic review

“…Regarding physiological responses, increases in skin conductance , heart rate (García- Rodríguez et al, 2013;Thompson-Lake et al, 2015), pre-frontal cortex activity (Lee et al, 2005), posterior EEG alpha power (Tamburin et al, 2021), and ocular fixations (Gamito et al, 2011;Liu, Stamos, Dewitte, van Berlo, & van der Laan, 2022) were found in cigarette smokers in response to virtual nicotine cue exposure.…”