In the era of Industry 4.0, remote monitoring and controlling appliance/equipment at home, institute, or industry from a long distance with low power consumption remains challenging. At present, some smart phones are being actively used to control appliances at home or institute using Internet of Things (IoT) systems. This paper presents a novel smart automation system using long range (LoRa) technology. The proposed LoRa based system consists of wireless communication system and different types of sensors, operated by a smart phone application and powered by a low-power battery, with an operating range of 3–12 km distance. The system established a connection between an android phone and a microprocessor (ESP32) through Wi-Fi at the sender end. The ESP32 module was connected to a LoRa module. At the receiver end, an ESP32 module and LoRa module without Wi-Fi was employed. Wide Area Network (WAN) communication protocol was used on the LoRa module to provide switching functionality of the targeted area. The performance of the system was evaluated by three real-life case studies through measuring environmental temperature and humidity, detecting fire, and controlling the switching functionality of appliances. Obtaining correct environmental data, fire detection with 90% accuracy, and switching functionality with 92.33% accuracy at a distance up to 12 km demonstrated the high performance of the system. The proposed smart system with modular design proved to be highly effective in controlling and monitoring home appliances from a longer distance with relatively lower power consumption.