Development and Implementation of Clinical Practice Guidelines: An Update and Synthesis of the Literature With a Focus in Application to Spinal Conditions

Abstract

Study Design: Review. Objectives: The objectives of this review are to ( a ) summarize the role of clinical practice guidelines (CPGs), ( b ) outline the methodology involved in formulating CPGs, ( c ) provide an illustration of these principles using a CPG developed for degenerative cervical myelopathy, and ( d ) highlight the importance of knowledge translation. Methods: A review of the literature was conducted to summarize current standards in CPG development and implementation. Results: CPGs are systematically developed statements intended to affect decisions made by health care providers, policy makers, and patients. The main objectives of CPGs are to synthesize and translate evidence into recommendations, optimize patient outcomes, standardize care, and facilitate shared decision making among physicians, patients, and their caregivers. The main steps involved in the development of CPGs include defining the clinical problem, assembling a multidisciplinary guideline development group and systematic review team, conducting a systematic review of the literature, translating the evidence to recommendations, critically appraising the CPG and updating the document when new studies arise. The final step in developing a CPG is to implement it into clinical practice; this step requires an assessment of the barriers to implementation and the formulation of effective dissemination strategies. Conclusion: CPGs are an important component in the teaching and practice of medicine and are available for a wide spectrum of diseases. CPGs, however, can only be used to influence clinical practice if the recommendations are informed by a systematic review of the literature and developed using rigorous methodology. The opportunity to transform clinical management of spinal conditions is an attractive outcome of the application of high-quality CPGs.

Systematic reviews in spinal cord injury: A step-by-step guide for rehabilitation science learners and clinicians

“… 32 The proliferating scientific evidence in SCI or disease requires parallel and ongoing synthesis of the most current research to inform clinical guidelines and healthcare policymaking. 33 We encourage ongoing rich evaluations of available literature by interprofessional SR teams in the field of SCI rehabilitation.…”

Clinical practice guideline for clozapine use in patients with COVID‐19

“…Guidelines aim to translate research into clinical practice to improve quality and safety of care 57,58 . This article highlights the need for increased awareness by clinicians of the complexity of challenge faced when prescribing clozapine in the context of COVID‐19 and emphasises the need for other NHS trusts to develop their own similar adapted clinical practice guidelines.…”

“…Guidelines aim to translate research into clinical practice to improve quality and safety of care. 57,58…”

Klinik Uygulamada Rehberler: Doğum Sonu Döneme Ait Örnekler

“…Klinik uygulama rehberi geliştirme basamakları Klinik uygulama rehberleri; zaman, emek ve ekip çalışması gerektiren sistematik bir dizi aşama sonrasında oluşturulmaktadır. Literatür incelemelerinde genel olarak rehber geliştirme konusunda öncü olan kuruluşların aşağıdaki basamakları kullandığı görülmektedir (7,8,26,27 (7).…”