Development and in vitro antiviral activity of ivermectin liposomes as a potential drug carrier system
Meryem Kocas,
Tansel Comoglu,
Aykut Ozkul
Abstract:This study aimed to assess and compare diverse formulations of ivermectin‐loaded liposomes, employing lipid film hydration and ethanol injection methods. Three lipids (DOPC, SPC, and DSPC) were used in predetermined molar ratios. A total of 18 formulations were created, and a factorial design determined the optimal formulation based on particle size, polydispersity index (PDI), zeta potential, and encapsulation efficiency. The average mean particle size, PDI and zeta potential of the selected formulations (F1,… Show more
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