Development and Validation of a Risk Calculator Predicting Postoperative Respiratory Failure

Gupta, Himani; Gupta, Prateek K.; Fang, Xiang; Miller, Weldon J.; Cemaj, Samuel; Forse, R. Armour; Morrow, Lee E.

doi:10.1378/chest.11-0466

Cited by 214 publications

(154 citation statements)

References 26 publications

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“…[11] Emergency surgery is a risk factor for RI, which has been validated in most of reports. [1,4,13] In this study, patients with RI had a prolonged length of intensive care unit stay, a prolonged length of hospitalization, an increased intensive care unit mortality rate, and a hospital mortality, which are similar to those reported by Franca et al [4] Patients with RI had a decreased one-year survival rate compared with those without RI. Although the precise cause of death was not clear, sequel plays an important role.…”

Section: Discussionsupporting

confidence: 86%

Risk factors and prognosis of critically ill cancer patients with postoperative acute respiratory insufficiency

Xing

Gao

Wang

et al. 2013

World Journal of Emergency Medicine

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BACKGROUND: This study aimed to investigate the risk factors and outcome of critically ill cancer patients with postoperative acute respiratory insuffi ciency. METHODS:The data of 190 critically ill cancer patients with postoperative acute respiratory insuffi ciency were retrospectively reviewed. The data of 321 patients with no acute respiratory insuffi ciency as controls were also collected. Clinical variables of the fi rst 24 hours after admission to intensive care unit were collected, including age, sex, comorbid disease, type of surgery, admission type, presence of shock, presence of acute kidney injury, presence of acute lung injury/acute respiratory distress syndrome, acute physiologic and chronic health evaluation (APACHE II) score, sepsis-related organ failure assessment (SOFA), and PaO 2 /FiO 2 ratio. Duration of mechanical ventilation, length of intensive care unit stay, intensive care unit death, length of hospitalization, hospital death and one-year survival were calculated. RESULTS:The incidence of acute respiratory insufficiency was 37.2% (190/321). Multivariate logistic analysis showed a history of chronic obstructive pulmonary diseases (P=0.001), surgeryrelated infection (P=0.004), hypo-volemic shock (P<0.001), and emergency surgery (P=0.018), were independent risk factors of postoperative acute respiratory insufficiency. Compared with the patients without acute respiratory insuffi ciency, the patients with acute respiratory insuffi ciency had a prolonged length of intensive care unit stay (P<0.001), a prolonged length of hospitalization (P=0.006), increased intensive care unit mortality (P=0.001), and hospital mortality (P<0.001). Septic shock was shown to be the only independent prognostic factor of intensive care unit death for the patients with acute respiratory insufficiency (P=0.029, RR: 8.522, B=2.143, SE=0.982, Wald=4.758). Compared with the patients without acute respiratory insufficiency, those with acute respiratory insuffi ciency had a shortened one-year survival rate (78.7% vs. 97.1%, P<0.001).CONCLUSION: A history of chronic obstructive pulmonary diseases, surgery-related infection, hypovolemic shock and emergency surgery were risk factors of critically ill cancer patients with postoperative acute respiratory insuffi ciency. Septic shock was the only independent prognostic factor of intensive care unit death in patients with acute respiratory insufficiency. Compared with patients without acute respiratory insufficiency, those with acute respiratory insufficiency had adverse shortterm outcome and a decreased one-year survival rate.

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Section: Discussionsupporting

confidence: 86%

Risk factors and prognosis of critically ill cancer patients with postoperative acute respiratory insufficiency

Xing

Gao

Wang

et al. 2013

World Journal of Emergency Medicine

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“…26,27 In this study, American Society of Anesthesiologists physical status served as a significant predictor of postoperative respiratory morbidity (OR, 27.2; p = 0.019). This finding is critical because this appeared to be the only reliable preoperative clinical variable predictive of respiratory morbidity.…”

Section: Discussionmentioning

confidence: 60%

Analysis of Risk Factors, Morbidity, and Cost Associated with Respiratory Complications following Abdominal Wall Reconstruction

Fischer

Wes

Wink

et al. 2014

Plastic and Reconstructive Surgery

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“…Among these patients, 2325 (2.5 %) developed PRF, defined as unplanned intubation or failure to wean from a ventilator more than 48 h after surgery [6,27,28]. Of patients who developed PRF, 1270 (54.6 %) were male, and the overall mean age was 60.59 years.…”

Section: Resultsmentioning

confidence: 99%

“…neurosurgical procedures are at a higher risk of PRF than other surgical specialties, including cardiac and orthopedics [1,[5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Risk factors for post-operative respiratory failure among 94,621 neurosurgical patients from 2006 to 2013: a NSQIP analysis

et al. 2016

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Development and Validation of a Risk Calculator Predicting Postoperative Respiratory Failure

Cited by 214 publications

References 26 publications

Risk factors and prognosis of critically ill cancer patients with postoperative acute respiratory insufficiency

Risk factors and prognosis of critically ill cancer patients with postoperative acute respiratory insufficiency

Analysis of Risk Factors, Morbidity, and Cost Associated with Respiratory Complications following Abdominal Wall Reconstruction

Risk factors for post-operative respiratory failure among 94,621 neurosurgical patients from 2006 to 2013: a NSQIP analysis

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