Development and Validation of a HPLC-UV Method for Urea and Related Impurities

Rapid and Direct Detection of Trimethylamine N-oxide Using an Off-Chip Capacitance Biosensor with Readout SoC for Early-Stage Thrombosis and Cardiovascular Disease

“…Historically, exploring metabolism necessitates costly laboratory equipment and specialized personnel, confining the research to large-scale laboratories. These methodologies predominantly encompass chromatography-based techniques such as gas chromatography–mass spectrometry (GC-MS), , flow injection gas diffusion-ion chromatography (FIGD-IC), high-performance liquid chromatography (HPLC), and ultrahigh-performance liquid chromatography-tandem mass spectrometry (UPLC-MS). , These approaches prove expensive and time-intensive, particularly for individuals preferring home-based healthcare, a preference exacerbated by events such as the COVID-19 pandemic, which enforced prolonged home stays. Lately, electrochemical sensors have emerged as a compelling substitute for analytical techniques in real-time monitoring.…”