Development and Validation of a Noninvasive Method to Determine Arterial Pressure and Vascular Compliance

Brinton, Todd J.; Cotter, Bruno; Kailasam, Mala T.; Brown, David L.; Chio, Shiu‐Shin; O’Connor, Daniel T.; DeMaria, Anthony N.

doi:10.1016/s0002-9149(97)00353-6

Cited by 126 publications

(99 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The measurements are submitted online to a central database (DynaPulse Analysis Center) for analysis and reporting. Pulse Metric's device has the advantage of validation of its BP and compliance measurements by correlation with invasive catheter measurements in the aorta (46). The DynaPulse 2000 has been used in clinical research to demonstrate the relationship between cardiovascular risk factors and coronary artery calcification (47,48).…”

Section: Office-based Devices That Measure Arterial Stiffnessmentioning

confidence: 99%

Vascular Stiffness

DeLoach

Townsend

2008

Clinical Journal of the American Society of Nephrology

241

185

View full text Add to dashboard Cite

Arterial stiffness is recognized increasingly as an important component in the determination of cardiovascular risk, particularly in chronic kidney disease and ESRD populations. Although the technique has been around for nearly 100 yr, in the past 20 to 25 yr, pragmatic noninvasive approaches have allowed the incorporation of arterial stiffness measurements, usually in the form of aortic pulse wave velocity (PWV), into clinical assessment of patients. In populations with high cardiovascular risk, especially those with ESRD, aortic PWV measurements provide predictive utility independent of the standard brachial arterial BP measurements. This review briefly discusses the history of vascular dynamics, the determinants of PWV, and some of the available technologies in current use and concludes with a section on the relevance of arterial stiffness measurements in populations of particular interest to nephrologists.

show abstract

Section: Office-based Devices That Measure Arterial Stiffnessmentioning

confidence: 99%

Vascular Stiffness

DeLoach

Townsend

2008

Clinical Journal of the American Society of Nephrology

241

185

View full text Add to dashboard Cite

show abstract

“…We have already used noninvasive data from Oscillometer and pulse volume recording (PVR); invasive data was taken from aorta and bronchial artery ( Figure 3). After getting data, we propose invasive and non-invasive degree of arterial compliance using a BlandAltman difference plot [15], t-test [16], box whisker plot [17] and scatter diagram [18].…”

Section: Waveform Computationmentioning

confidence: 99%

Comparative Study of Arterial Compliance Using Invasive and Noninvasive Blood Pressure Waveform

Chen¹,

Singh²,

Hu³

2017

JBET

View full text Add to dashboard Cite

Most of the epidemiological studies have shown a good relationship between blood pressure and manifestation of cardiovascular diseases (CVD). CVD has become a very common health condition that exhibits significant changes in distensibilility, compliance, and elastic modulus of the arterial vascular system. The main causes of this disease are the spreading of fats and cholesterols which initiate the damaging of endothelium, decreasing wall buffering capacity, and hardening of the arteries eventually leading to severe narrowing. We compared data from invasive and non-invasive blood pressure wave form. Using the Windkessel model, to estimate the arterial compliance as vascular index, we used data after the aortic valve closed to the end-diastolic point of blood pressure waveforms, utilized Bland-Altman difference plot, T-test, box whisker plot and scatter diagram. We analyzed physiological real data and investigated the correlation between the non-invasive and invasive blood pressure wave form. Non-invasive compressive pulse waveforms can be used to assess the total compliance of the arterial blood pressure waveforms of the invasive aorta that indicates the buffering of muscle and adipose tissue.

show abstract

“…Peripheral maximum dP/dt calculations are correlated with invasive measurements of left ventricular dP/dt max (r=0.87). 17 Left ventricular dP/dt is an attractive, robust, and sensitive indicator of changes in cardiac contractility. 18 Left ventricular dP/dt can be influenced by heart rate, but this was unchanged in the present study as was its load dependency.…”

Section: Potential Mechanisms Of Actionmentioning

confidence: 99%

Dietary Flaxseed Reduces Central Aortic Blood Pressure Without Cardiac Involvement but Through Changes in Plasma Oxylipins

et al. 2016

View full text Add to dashboard Cite

Abstract-In the year-long FlaxPAD clinical trial (Flaxseed for Peripheral Artery Disease), dietary flaxseed generated a powerful reduction in brachial systolic and diastolic blood pressure in patients with peripheral artery disease. Oxylipins were implicated as potential mechanistic mediators. However, the ability of flaxseed to impact central aortic hypertension, arterial stiffness, or cardiac performance was not investigated. Additionally, the relationship between central blood pressure (cBP) and oxylipins was not elucidated. Therefore, radial tonometry and pulse wave analysis were used to measure cBP and cardiac function in the FlaxPAD population (n=62). Plasma oxylipins were analyzed with high-performance liquid chromatography mass spectrometry. In patients with high blood pressure at baseline, the average decrease in central systolic and diastolic blood pressures versus placebo was 10 and 6 mm Hg, respectively. Flaxseed did not significantly impact augmentation index or other cardiac function indices. Alternatively, the data support several specific oxylipins as potential mediators in the antihypertensive properties of flaxseed. For example, every 1 nmol/L increase in plasma 16-hydroxyeicosatetraenoic acid increased the odds of higher central systolic and diastolic blood pressures by 12-and 9-fold, respectively. Every 1 nmol/L increase in plasma thromboxane B 2 and 5,6-dihydroxyeicosatrienoic acid increased the odds of higher cBP by 33-and 9-fold, respectively. Flaxseed induced a decrease in many oxylipins, which corresponded with a reduced risk of elevated cBP. These data extend the antihypertensive properties of flaxseed to cBP without cardiac involvement but rather through oxylipins. This study provides further support for oxylipins as therapeutic targets in hypertension. Clinical Trial Registration-URL: http://www.clinicaltrials.gov. Unique identifier: NCT00781950.

show abstract

Development and Validation of a Noninvasive Method to Determine Arterial Pressure and Vascular Compliance

Cited by 126 publications

References 15 publications

Vascular Stiffness

Vascular Stiffness

Comparative Study of Arterial Compliance Using Invasive and Noninvasive Blood Pressure Waveform

Dietary Flaxseed Reduces Central Aortic Blood Pressure Without Cardiac Involvement but Through Changes in Plasma Oxylipins

Contact Info

Product

Resources

About