Development and validation of a multidimensional questionnaire for evaluating quality of life in melasma (HRQ-melasma)

Pollo, Camila Fernandes; Miot, Luciane Donida Bartoli; Meneguin, Silmara; Miot, Hélio Amante

doi:10.1590/abd1806-4841.20186780

Cited by 11 publications

(17 citation statements)

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“…Due to the wide utilization of the MELASQoL scale there were problems such as difficulty in semantic interpretation, no prior qualitative analysis of disease perception, and low representation of feelings and self-esteem dimensions [ 38 , 39 ]. To address these issues, in 2018, a multidimensional tool was developed and verified [ 38 ]. Comparing the MELASQoL scale with this new multidimensional tool may provide a more in-depth understanding of the impact of melasma on patients’ quality of life.…”

Section: Discussionmentioning

confidence: 99%

Evaluating the quality of life among melasma patients using the MELASQoL scale: A systematic review and meta-analysis

et al. 2022

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Background According to the literature, pigmentary disorders have a significantly negative impact on a person’s health-related quality of life. Moreover, among pigmentary disorders, incidence of melasma ranks high. The Melasma Area and Severity Index (MASI) is the scale that is generally used to evaluate a melasma-affected area and its severity. However, the relationship between the MASI and Melasma Quality of Life (MELASQoL) scores, as well as the impact of melasma on patients’ quality of life, remain unclear. Objectives To explore the influence of melasma on patients’ lives, analyze the relationship between the MASI and MELASQoL scores, and identify the factors that may be influencing the quality of life of patients with melasma. Methods Two reviewers independently searched four databases (PubMed, Embase, the Cochrane Library, and Web of Science) for literature on quality of life of patients with melasma. In addition to an epidemiological study, a cross-sectional study, and validation studies, gray literature was also included. StataSE version 16 software was used for the meta-analysis. The score of each item on the MELASQoL scale was determined using a random-effects model. Results Fourteen studies with a total of 1398 melasma patients were included in the systematic review, four of which were eligible for meta-analysis. The relationship between the MELASQoL and MASI scores was found to be mixed. Five studies concluded that the MASI and MELASQoL scores were statistically correlated, while seven studies found no statistical correlation between the two. It is obvious that melasma causes emotional distress and has a negative impact on patients’ social lives. Patients were most bothered by the appearance of their skin condition. However, the MELASQoL score had no definite correlation with patient characteristics such as age, education levels, and history. Conclusion Melasma has a significant negative impact on patients’ quality of life. Thus, evaluating the quality of life of patients with melasma should not be ignored. Additionally, utilization of the MELASQoL scale should be considered in the care plan. Further studies with larger sample sizes are needed to confirm the relationship between melasma and quality of life.

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Section: Discussionmentioning

confidence: 99%

Evaluating the quality of life among melasma patients using the MELASQoL scale: A systematic review and meta-analysis

et al. 2022

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“…The predominantly mild to moderate impact on HRQOL is common in dermatological series and requires instruments with su cient discrimination in this impact range. (4,11,(27)(28)(29)(30)(31)(32)(33) The three instruments studied demonstrated adequate feasibility, internal consistencies, temporal stability, and sensitivity to change. The Sk-17 subscale of symptoms exhibited small psychometric indicators.…”

Section: Discussionmentioning

confidence: 99%

“…(4) There are ve possible answers for each item (very much, a lot, a little, not at all, and not relevant); the score for each item ranges from 0 to 3. (2-5) Conventionally, DLQI scores are interpreted based on the algebraic sum of the indexes of the 10 items evaluated: without compromising quality of life (0-1), with mild (2-5), moderate (6-10), severe (11)(12)(13)(14)(15)(16)(17)(18)(19)(20), or very severe (21)(22)(23)(24)(25)(26)(27)(28)(29)(30) impairment. (6)…”

Section: Introductionmentioning

confidence: 99%

Psychometric Comparison of the Performance of Quality of Life Assessment Instruments in Dermatology—the DLQI, Skindex-16, and Skindex-17—in a Brazilian Population.

Mfs

et al. 2021

Preprint

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Background: The DLQI (Dermatology Life Quality Index) is the most commonly used instrument for evaluating the quality of life in dermatology. Skindex was developed as a multidimensional instrument with successive versions published, the most recent being Skindex-16 and Skindex-17, both derived from Skindex-29 through different techniques. This study aimed to compare the three instruments—the DLQI, Skindex-16, and Skindex-17—according to their psychometric performance to refine the assessment of the quality of life among dermatological patients.Methods: A methodological study compared the psychometric performance of the DLQI, Skindex-16 (Sk-16), and Skindex-17 (Sk-17) instruments among adults with dermatoses that were classified according to characteristic physical symptoms and psychological or social domains. Analyses were performed to assess internal consistency, correlation, test-retest reproducibility, and responsiveness according to classical psychometry and to test discrimination and difficulty according to the item response theory.Results: The sample consisted of 229 patients predominantly women (71%) of adult age (average 45 years) and intermediate phototypes (III and IV = 73%). The analyses of internal consistency for the instruments resulted in Cronbach-α coefficients >0.80. There was adequate test-retest reproducibility and responsiveness for all dimensions of the instruments. The IRT (Iten Response Theory) analysis indicated adequate ordering and discrimination (a >1.0) for all items of the DLQI, Sk-16, and Sk-17; four items of Sk-16 did not adequately adhere to the TRI model (p <0.01 ). The items with the greatest discrimination were q3 (domestic activities) and q5 (leisure activities) in the DLQI; F2 (desire to be with people) and E6 (annoyance) in Sk-16; and S4 (irritated skin), P5 (relationship), and P6 (autonomy of tasks) in Sk-17. The Sk-16 and Sk-17 instruments presented more items that registered mild impacts on the quality of life (b <-0.5).Conclusions: The DLQI, Sk-16, and Sk-17 presented adequate psychometric performance for the assessment of health-related quality of life in a Brazilian sample. The multidimensional instruments (Sk-16 and Sk-17) were more sensitive to mild impacts on quality of life.

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“…Melasma is a pigmentary skin disorder characterized by the presence of hyperchromia, asymptomatic and symmetrical macules in the skin [ 1 , 2 ]. These macules molecules are formed due to local hypermelanogenesis and typically appear on the face in central locations such as cheeks, chin, nose, and upper lip [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

“…In contrast, disease-specific instruments focus on a specific area of interest, detecting biological and psychosocial aspects of a specific condition. For the purpose of this study, the HRQ-Melasma was selected to assess the disease-specific QOL as this instrument was developed specifically for individuals with melasma [ 1 ]. The advantage of these instruments is that they are sensitive enough to detect specific aspects of a disease's impact on the QOL [ 19 ].…”

Section: Introductionmentioning

confidence: 99%

Comparison of generic and specific instruments to assess the quality of life in patients with melasma

Meneguin

Mourão

Pollo

et al. 2022

BMC Med Res Methodol

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Objective To compare the psychometric performance of a generic and specific instruments in assessing melasma-related quality of life. Methods A cross-sectional study was conducted with 150 patients with melasma attending an outpatient dermatology clinic of a public hospital in São Paulo state, Brazil. Data were collected using a questionnaire containing sociodemographic and clinical data as well as the generic WHOQOL-BREF, and the dermatological-specific Skindex-16 and HRQ-Melasma. Results The overall internal consistency of the domains of the three instruments was ≥ 0.7. A strong positive correlation was identified between the Skindex-16 and HRQ-Melasma domains (0.68-0.78). Item-response theory showed that most Skindex-16 and HRQ-Melasma domains were more informative than WHOQOL-BREF. Conclusion The three instruments for assessing QOL tested presented good psychometric performance, with satisfactory internal consistency values. Only the two dermatological instruments, however, demonstrated a strong correlation between the domains that assess social, emotional, and functional aspects of QOL, indicating that both were able to identify impairments in other QOL dimensions in addition to the physical domain.

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Development and validation of a multidimensional questionnaire for evaluating quality of life in melasma (HRQ-melasma)

Cited by 11 publications

References 30 publications

Evaluating the quality of life among melasma patients using the MELASQoL scale: A systematic review and meta-analysis

Evaluating the quality of life among melasma patients using the MELASQoL scale: A systematic review and meta-analysis

Psychometric Comparison of the Performance of Quality of Life Assessment Instruments in Dermatology—the DLQI, Skindex-16, and Skindex-17—in a Brazilian Population.

Comparison of generic and specific instruments to assess the quality of life in patients with melasma

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