Abstract:Background: Cutaneous melanoma is cancer that is both malignant and aggressive, with a poor prognosis. Pyroptosis can affect the prognosis of cancer patients by controlling tumor cell growth, migration, and metastasis, as well as is closely related to the tumor immune microenvironment. The significance of pyroptosis-related genes (PRGs) in cutaneous melanoma, however, is unknown. Methods: The training set and external validation sets were cutaneous melanoma samples from The Cancer Genome Atlas (TCGA) database … Show more
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