Development and validation of a fast static headspace GC method for determination of residual solvents in permethrin

Tian, Jiangwei; Rustum, Abu M.

doi:10.1016/j.jpba.2016.06.020

Cited by 16 publications

(4 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Permethrin, (±)-3-Phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate, is another synthetic pyrethroid which has broadly used to kill dreadful mosquitoes to prevent several diseases associated with mosquitoes such as malaria, dengue, and lymphatic filariasis [9,10]. Besides, this pyrethroid is also used as a pharmaceutical ingredient for human and veterinary drugs [11]. Nevertheless, permethrin was found to be toxic to humans in case of inhalation or even dermal absorption.…”

Section: Introductionmentioning

confidence: 99%

Optimized three‐phase hollow fiber liquid‐phase automated microextraction and its application in ultra‐trace analysis of three pyrethroids in water and fruit samples using high‐performance liquid chromatography‐diode array detection

Nikdel,

Nezami,

Yamini

et al. 2024

Separation Science Plus

View full text Add to dashboard Cite

In the present manuscript, an automated three‐phase hollow fiber liquid‐phase microextraction followed by high‐performance liquid chromatography‐diode array detection is applied for the extraction and determination of three pyrethroids, deltamethrin, fenpropathrin, and permethrin in water and fruit samples. N‐dodecane was selected as a supported liquid membrane (SLM) and its polarity was adjusted by trioctylphosphine oxide one‐variable‐at‐a‐time method was used in order to achieve optimal hollow fiber liquid‐phase microextraction parameters such as type of organic acceptor phase, the composition of SLM, ionic strength of sample solution, extraction time, length of hollow fibers and stirring speed. Under the optimal conditions, the calibration curves for the three pyrethroids were plotted, and figures of merit of the proposed method were calculated. The linear dynamic ranges were in the range of 0.9–200, 0.75–200, and 1.5–200 μg/L for deltamethrin, fenpropathrin, and permethrin, with the coefficient of determination better than 0.998. The limits of detection were in the range of 0.3, 0.25, and 0.5 and the limits of quantification were in the range of 0.9, 0.75, and 1.5 μg/L for deltamethrin, fenpropathrin, and permethrin, respectively. The precision of the method was evaluated in terms of relative standard deviation at two different concentration levels 10 and 50 μg/L. The results of real sample analysis in cucumber exhibited high sensitivity, excellent sample clean‐up, favorable repeatability, and suitable accuracy.

show abstract

Section: Introductionmentioning

confidence: 99%

Optimized three‐phase hollow fiber liquid‐phase automated microextraction and its application in ultra‐trace analysis of three pyrethroids in water and fruit samples using high‐performance liquid chromatography‐diode array detection

Nikdel,

Nezami,

Yamini

et al. 2024

Separation Science Plus

View full text Add to dashboard Cite

show abstract

“…Several headspace techniques such as static headspace (SHS) [7][8][9][10][11], dynamic headspace [12] and headspace solid phase microextraction [5,13] can be employed. Static headspace analysis is probably the most widely used technique for residual solvent analysis in pharmaceuticals as it is inexpensive, easy to perform and automate, can be successfully used routinely in control labs.…”

Section: Introductionmentioning

confidence: 99%

“…The nature of the matrix medium is of primary importance as has an essential influence on the amount of the analytes in the headspace and thus on the determination sensitivity. For residual solvents determination in pharmaceuticals, water [8], dimethylsulfoxide [9,15], N,N-dimethylacetamide [16], N,N-dimethylformamide (DMF) [15], benzyl alcohol [17], liquid paraffin [18] and ionic liquids [3,11] were suggested as matrix media. Recently, for residual solvents determination deep eutectic solvents (DESs) have been proposed [7,8,19].…”

Section: Introductionmentioning

confidence: 99%

Headspace gas chromatographic analysis of residual solvents in pharmaceuticals: comparison of two matrix media

Vičkačkaitė¹,

Jevtuch²,

Poškus³

et al. 2020

chemija

View full text Add to dashboard Cite

Dimethylformamide (DMF) and a deep eutectic solvent choline chloride-ethylene glycol (ChCl-Eg) were investigated as potential matrix media for static headspace gas chromatographic (SHS-GC) determination of residual solvents in pharmaceuticals. Sample equilibration temperature, equilibration time and injection time were optimized. In the case of DMF 140°C equilibration temperature was applied. For ChCl-Eg equilibration temperature could not exceed 80°C as ChCl-Eg started to degrade at elevated temperatures. The higher equilibration temperature of DMF solutions favoured a transition of the analytes to the headspace and consequently resulted in lower detection limits of the analytes. Thus DMF has been considered a more suitable matrix medium than ChCl-Eg and was applied for the SHS-GC determination of residual solvents in pharmaceuticals.

show abstract

“…One of the important works is exploring the superior dilution matrix. Except for the traditionally used dilution matrix of dimethyl sulfoxide (DMSO), dimethylacetamide (DMA), and water, many other high boiling solvents, such as paraffin and ionic liquids, have also been used as SHS matrix medium [23,24,25,26]. Recently, we successfully introduced another new type of green solvent natural deep eutectic solvents (NADESs) into SHS for the analysis of residue solvents in pharmaceuticals [27].…”

Section: Introductionmentioning

confidence: 99%

Headspace Gas Chromatography-Mass Spectrometry for Volatile Components Analysis in Ipomoea Cairica (L.) Sweet Leaves: Natural Deep Eutectic Solvents as Green Extraction and Dilution Matrix

Zhang

Liang

2019

Foods

View full text Add to dashboard Cite

In this study, natural deep eutectic solvents (NADESs) were used as both the extraction and dilution matrix in static headspace gas chromatography-mass spectrometry (SHS-GC-MS) for the analysis of volatile components in Ipomoea cairica (L). Sweet (ICS) leaves. Six NADESs were prepared and the NADESs composed of choline chloride and glucose with a 1:1 molar ratio containing 15% water were preferred due to the better peak responses. A total of 77 volatiles in ICS leaves were detected and tentatively identified by mass spectral matching with the US National Institute of Standards and Technology (NIST, 2014) Mass Spectral Library and the retention index-assisted qualitative method. These 77 volatile components were mainly terpenoids, aromatics, and aliphatics. Among them, β-elemene, β-caryophyllene, α-humulene, and 2, 4-di-tert-butylphenol were found to be the main components. This investigation verified that the use of NADESs is an efficient green extraction and dilution matrix of the SHS-GC-MS method for direct volatile component analysis of plant materials without extra extraction work.

show abstract

Development and validation of a fast static headspace GC method for determination of residual solvents in permethrin

Cited by 16 publications

References 11 publications

Optimized three‐phase hollow fiber liquid‐phase automated microextraction and its application in ultra‐trace analysis of three pyrethroids in water and fruit samples using high‐performance liquid chromatography‐diode array detection

Optimized three‐phase hollow fiber liquid‐phase automated microextraction and its application in ultra‐trace analysis of three pyrethroids in water and fruit samples using high‐performance liquid chromatography‐diode array detection

Headspace gas chromatographic analysis of residual solvents in pharmaceuticals: comparison of two matrix media

Headspace Gas Chromatography-Mass Spectrometry for Volatile Components Analysis in Ipomoea Cairica (L.) Sweet Leaves: Natural Deep Eutectic Solvents as Green Extraction and Dilution Matrix

Contact Info

Product

Resources

About