2023
DOI: 10.3389/fmed.2023.1193133
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Development and validation of prognostic index based on purine metabolism genes in patients with bladder cancer

Zixuan Wu,
Ziqing Feng,
Hongyan Wei
et al.

Abstract: BackgroundBladder cancer (BLCA) is a prevalent malignancy affecting the urinary system and is associated with significant morbidity and mortality worldwide. Dysregulation of tumor metabolic pathways is closely linked to the initiation and proliferation of BLCA. Tumor cells exhibit distinct metabolic activities compared to normal cells, and the purine metabolism pathway, responsible for providing essential components for DNA and RNA synthesis, is believed to play a crucial role. However, the precise involvement… Show more

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