Development and validation of two robust simple chromatographic methods for estimation of tomatoes specific pesticides’ residues for safety monitoring prior to food processing line and evaluation of local samples

Hegazy, Amira M.; Abdelfatah, Rehab M.; Mahmoud, Hamada M.; Elsayed, Mohamed A.

doi:10.1016/j.foodchem.2019.125640

Cited by 15 publications

(5 citation statements)

References 18 publications

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“…The development of specific methods of analysis for a mixture of little definite insecticides and/or fungicides is a new trend in residual assessment for food and environmental analysis 1 – 3 . The authors have been working consistently since early 2017 using this strategy starting with extensive studies concerning specific insecticide residues on cucumbers 4 , 5 . And here, we are following the same concern extending our work on a different blend of the insecticides 6 , 7 and the concerned substances [hiexythiazox (HTX), imidacloprid (IDD), and thiamethoxam (TTM)] by spectrophotometric techniques 8 .…”

Section: Introductionmentioning

confidence: 99%

Applying novel economic simple green sample preparation procedures on natural and industrial specimens for chromatographic determination of insecticidal residues

Hegazy

Mahmoud

Elsayed

et al. 2023

Sci Rep

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Spraying a tertiary blend of the insecticides (hexythiazox, imidacloprid, and thiamethoxam), on tomato fruits, is a routine in agriculture-attentive countries. A simple green sample preparation technique was developed and applied to the field samples. Specific HP-TLC and RP-HPLC methodologies are established to estimate the residual insecticides and applied to the prepared field specimens. In the planner chromatographic methodology, methanol:chloroform:glacial acetic acid:triethyl amine (8.5:1.5:0.2:0.1, v/v) is recommended as a mobile system. The other one is columnar chromatography; acetonitrile: water (20:80, v/v), pH 2.8, is recommended as a mobile system. The validation parameters were examined following the ICH rules. The means percentages and standard deviations of the accuracy of the HP-TLC method for the determined compounds were 99.66 ± 0.974, 99.41 ± 0.950, and 99.89 ± 0.983, correspondingly. The values were 99.24 ± 0.921, 99.69 ± 0.681, and 99.20 ± 0.692, correspondingly, when they were determined by the RP-HPLC method. The relative standard deviation percentages of the methods’ repeatability and intermediate precision ranged from 0.389 to 0.920. Both methods were highly specific having resolution factors of ≥ 1.78 and selectivity factors of ≥ 1.71. They were applied to the field samples perfectly.

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Section: Introductionmentioning

confidence: 99%

Applying novel economic simple green sample preparation procedures on natural and industrial specimens for chromatographic determination of insecticidal residues

Hegazy

Mahmoud

Elsayed

et al. 2023

Sci Rep

Self Cite

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“…High performance liquid chromatography (HPLC) is one of the most frequently used techniques for the determination of drugs, [1][2][3][4][5][6][7][8] natural products, [9][10][11][12][13] foods, [14][15][16][17][18] and important environmental markers. [19][20][21][22][23][24] Quality control analysis is a vital step to ensure correct dosage during production, but the routine analysis for each pharmaceutical formulation alone results in a large amount of hazardous chemical waste.…”

Section: Introductionmentioning

confidence: 99%

A new green approach for the reduction of consumed solvents and simultaneous quality control analysis of several pharmaceuticals using a fast and economic RP-HPLC method; a case study for a mixture of piracetam, ketoprofen and omeprazole drugs

et al. 2022

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“…Thus, the risk caused by pesticide residues in the final consumption of food could be calculated by monitoring the raw agricultural products combined with PFs [6]. However, it is difficult to evaluate all the PFs due to the diverse ways of food consumption [7]. Moreover, the risk caused by the transformation of parent pesticides into toxic metabolites was ignored [8].…”

Section: Introductionmentioning

confidence: 99%

Ethanol‐ammonium sulfate system based modified quick, easy, cheap, effective, rugged, and safe method for the determination of four neonicotinoid pesticide and metabolite residues in two canned fruits

Chen

Huang

et al. 2022

J of Separation Science

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As the pesticide and its metabolite residues in processed fruits could become a significant route of human exposure. The work presented herein focuses on developing a feasible quick, easy, cheap, effective, rugged, and safe method with improved extraction and cleanup system for the determination of imidacloprid, acetamiprid, thiamethoxam, and clothianidin (a metabolite of thiamethoxam) in canned fruits. The low toxic solvent ethanol was used to extract the analytes, and ammonium sulfate was used to promote phase separation. Moreover, the carboxylated multi‐walled carbon nanotube acted as the clean‐up sorbent for the removal of high solubility impurities. The proposed method was validated with fortified real samples at different concentration levels (20–200 μg/kg). Recoveries obtained from three spiked levels (20, 50, and 200 μg/kg) ranged from 74.9 to 86.4% with relative standard deviations of the intra‐day and inter‐day in the range of 0.8–5.5 and 2.0–7.1%, respectively. The limits of detection ranged from 0.2 to 0.5 and 0.2 to 0.6 μg/kg for orange and peach, respectively. The results demonstrated that the proposed method could be considered appropriate, and comparatively lower toxic for the analysis of neonicotinoid pesticide residues in canned fruit.

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Development and validation of two robust simple chromatographic methods for estimation of tomatoes specific pesticides’ residues for safety monitoring prior to food processing line and evaluation of local samples

Cited by 15 publications

References 18 publications

Applying novel economic simple green sample preparation procedures on natural and industrial specimens for chromatographic determination of insecticidal residues

Applying novel economic simple green sample preparation procedures on natural and industrial specimens for chromatographic determination of insecticidal residues

A new green approach for the reduction of consumed solvents and simultaneous quality control analysis of several pharmaceuticals using a fast and economic RP-HPLC method; a case study for a mixture of piracetam, ketoprofen and omeprazole drugs

Ethanol‐ammonium sulfate system based modified quick, easy, cheap, effective, rugged, and safe method for the determination of four neonicotinoid pesticide and metabolite residues in two canned fruits

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