Development of a 3D optical scanner for evaluating patient-specific dose distributions

Chang, Kyung Hwan; Lee, Suk; Jung, Hong Ryang; Choo, Yeon Wook; Cao, Yuan; Shim, Ju Hyun; Kim, Kwang Hyeon; Lee, Nam Kwon; Park, Young Je; Kim, Chul Yong; Cho, Sam Ju; Lee, Sang Hoon; Min, Chul Kee; Kim, Woo Chul; Cho, Kwang Hwan; Huh, Hyun Do; Lim, Sangwook

doi:10.1016/j.ejmp.2015.05.009

Cited by 8 publications

(4 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Section: Introductionmentioning

confidence: 99%

“…Pretreatment patient-specific delivery quality assurance (DQA) is essential for the verification of accurate dose delivery in advanced radiation therapy techniques, such as intensitymodulated radiation therapy (IMRT), volumetric modulated arc therapy, stereotactic body radiation therapy, and helical tomotherapy (HT). [1][2][3][4] An HT system is an IMRT delivery system that delivers the radiation beam with a high degree of conformity; it is an imageguided system using megavoltage computed tomography (CT). 5 The radiation beam is delivered using a 6-MV linear accelerator continually while the couch is moving into the gantry, and intensity modulation is achieved with a binary multileaf collimator (MLC).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Statistical Analysis of Treatment Planning Parameters for Prediction of Delivery Quality Assurance Failure for Helical Tomotherapy

Chang

Lee²,

Park³

et al. 2020

Technol Cancer Res Treat

Self Cite

View full text Add to dashboard Cite

Purpose: This study aimed to investigate the parameters with a significant impact on delivery quality assurance (DQA) failure and analyze the planning parameters as possible predictors of DQA failure for helical tomotherapy. Methods: In total, 212 patients who passed or failed DQA measurements were retrospectively included in this study. Brain (n = 43), head and neck (n = 37), spinal (n = 12), prostate (n = 36), rectal (n = 36), pelvis (n = 13), cranial spinal irradiation and a treatment field including lymph nodes (n = 24), and other types of cancer (n = 11) were selected. The correlation between DQA results and treatment planning parameters were analyzed using logistic regression analysis. Receiver operating characteristic (ROC) curves, areas under the curves (AUCs), and the Classification and Regression Tree (CART) algorithm were used to analyze treatment planning parameters as possible predictors for DQA failure. Results: The AUC for leaf open time (LOT) was 0.70, and its cut-off point was approximately 30%. The ROC curve for the predicted probability calculated when the multivariate variable model was applied showed an AUC of 0.815. We confirmed that total monitor units, total dose, and LOT were significant predictors for DQA failure using the CART. Conclusions: The probability of DQA failure was higher when the percentage of LOT below 100 ms was higher than 30%. The percentage of LOT below 100 ms should be considered in the treatment planning process. The findings from this study may assist in the prediction of DQA failure in the future.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Statistical Analysis of Treatment Planning Parameters for Prediction of Delivery Quality Assurance Failure for Helical Tomotherapy

Chang

Lee²,

Park³

et al. 2020

Technol Cancer Res Treat

Self Cite

View full text Add to dashboard Cite

show abstract

“…Aqueous solution of Alizarin yellow GG (AY-GG) undergoes degradation under the effect of radiation (Sun et al , 2013). In the present study, murexide, a reddish-purple compound, has received much interest because of its application in chemical analysis and spectrophotometric fields (Abtahi and Poughanbari, 2018; Chang et al , 2015).…”

Section: Introductionmentioning

confidence: 99%

Radiation induced degradation of murexide dye in two media for possible use in dosimetric applications

Gafar

Abdel-Kader

2019

PRT

View full text Add to dashboard Cite

Purpose The purpose of this paper is to study the effect of gamma-rays on murexide (Mx) dye and its possible use as radiation dosimeters in two different dosimetry systems. The first system depends on the Mx dye as a liquid dosimeter. The second dosimetry system depends also on the same dye but as in a gel form, which is more sensitive to gamma-rays. Design/methodology/approach The prepared Mx (solutions/gels) have a considerable two peaks at 324 and 521 nm that upon irradiation, the intensity of these peaks decreases with the increasing radiation dose. Findings The gamma-ray absorbed dose for these dosimeters was found to be up to 2 kGy for the solution samples and 40 Gy for the gels. Radiation chemical yield, dose response function, radiation sensitivity and before and after-irradiation stability under various conditions were discussed and studied. Practical implications It is expected that the radiolysis of the Mx dye can be used as radiation dosimeters in two different dosimetry systems; liquid and gel dosimeters. This can be applied in a wide range of gamma radiation practical industrial applications in water treatment, food irradiation dosimeters, radiotherapy and fresh food irradiation and seed production. Originality/value Both of the prepared Mx dyes, either as solutions or gel samples, can be facilely prepared from commercially, cheap, safe, available chemicals and suitable for useful applied Mx solutions and gels radiation dosimeters.

show abstract

“…Scan speed was 10 slices min −1 , giving a 5 min acquisition time for a typical 50 slice scan of voxel size 0.3 × 0.3 × 1.0 mm, or 17 min for 0.3 mm isotropic voxels. This level of acquisition time is comparable to broad beam scanners (Olding et al 2010, Thomas et al 2011, although a sub-minute cone beam scanner has been recently reported (Chang et al 2016).…”

Section: Optical Ct Scanner Designmentioning

confidence: 67%

A fast dual wavelength laser beam fluid-less optical CT scanner for radiotherapy 3D gel dosimetry I: design and development

Ramm

2018

Phys. Med. Biol.

View full text Add to dashboard Cite

Three dimensional dosimetry by optical CT readout of radiosensitive gels or solids has previously been indicated as a solution for measurement of radiotherapy 3D dose distributions. The clinical uptake of these dosimetry methods has been limited, partly due to impracticalities of the optical readout such as the expertise and labour required for refractive index fluid matching. In this work a fast laser beam optical CT scanner is described, featuring fluid-less and dual wavelength operation. A second laser with a different wavelength is used to provide an alternative reference scan to the commonly used pre-irradiation scan. Transmission data for both wavelengths is effectively acquired simultaneously, giving a single scan process. Together with the elimination of refractive index fluid matching issues, scanning practicality is substantially improved. Image quality and quantitative accuracy were assessed for both dual and single wavelength methods. The dual wavelength scan technique gave improvements in uniformity of reconstructed optical attenuation coefficients in the sample 3D volume. This was due to a reduction of artefacts caused by scan to scan changes. Optical attenuation measurement accuracy was similar for both dual and single wavelength modes of operation. These results established the basis for further work on dosimetric performance.

show abstract

Development of a 3D optical scanner for evaluating patient-specific dose distributions

Cited by 8 publications

References 16 publications

Statistical Analysis of Treatment Planning Parameters for Prediction of Delivery Quality Assurance Failure for Helical Tomotherapy

Statistical Analysis of Treatment Planning Parameters for Prediction of Delivery Quality Assurance Failure for Helical Tomotherapy

Radiation induced degradation of murexide dye in two media for possible use in dosimetric applications

A fast dual wavelength laser beam fluid-less optical CT scanner for radiotherapy 3D gel dosimetry I: design and development

Contact Info

Product

Resources

About