Development of a core descriptor set for Crohn's anal fistula

Williams, Kate; Lamidi, Segun; Coe, Peter; Bordeianou, Liliana; Hart, Ailsa; Hind, Daniel; Lindsay, James O.; Lobo, Alan; Myrelid, Pär; Raine, Tim; Sebastian, Shaji; Fearnhead, Nicola; Lee, Matthew J.; Adams, Katie; Almér, Sven; Ananthakrishnan, Ashwin N.; Bethune, Robert; Block, Mattias; Brown, Steven R.; Cirocco, William C.; Cooney, Rachel; Davies, Justin; Atici, S D; Dhar, Anjan; Din, Shahida; Drobne, David; Espín‐Basany, Eloy; Evans, Jonathan P; Fleshner, Phillip; Folkesson, Joakim; Fraser, Aileen; Graf, Wilhelm; Hahnloser, Dieter; Hager, Jakob; Hancock, Laura; Hanžel, Jurij; Hargest, Rachel; Hedin, Charlotte; Hill, James A.; Ihle, Christof; Jongen, Johannes; Kader, Rawen; Karmiris, Konstantinos; Κατσάνος, Κωνσταντίνος; Keller, Debby S.; Kopylov, Uri; Koutrabakis, Ioannis E.; Lamb, Chris A.; Landerholm, Kalle; Lee, Grace C.; Litta, Francesco; Limdi, Jimmy K.; Lopes, Emily W.; Madoff, Robert D.; Martin, Seán T.; Martin‐Perez, Beatriz; Michalopoulos, George K.; Millán, Mónica; Münch, Andreas; Nakov, Radislav; Noor, Nurulamin M; Øresland, Tom; Paquette, Ian M.; Pellino, Gianluca; Perra, Teresa; Porcu, Alberto; Roslani, April Camilla; Samaan, Mark A; Sebepos‐Rogers, G. M.; Segal, Jontahan P.; Silva, Shanika de; Söderholm, Mattias; Spinelli, Antonino; Speight, R Alexander; Steinhagen, Randolph; Stenström, Pernilla; Tsimogiannis, Konstantinos E; Varma, Mika G.; Verma, Ajay; Verstockt, Bram; Warden, Claire; Yassin, Nuha; Zawadzki, Antoni; Carr, Paula; Devlin, Brian; Mannick, S; Avery, Pearl; Gecse, Krisztina; Goren, Idan; Hellström, Per M.; Kotze, Paulo Gustavo; McWhirter, D.; Naik, Amar S.; Sammour, Tarik; Selinger, Christian P.; Stein, Sharon L.; Torres, Joana; Wexner, Steven D.; Younge, Lisa

doi:10.1111/codi.16440

Cited by 7 publications

(3 citation statements)

References 30 publications

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“…Of the 37 ENiGMA core descriptors, a median of 15 were presented per study (IQR [13][14][15][16][17][18]. Sixteen descriptors were used in over 50% of studies, while 17 or more descriptors were present in fewer than 33% of studies.…”

Section: Re Sultsmentioning

confidence: 99%

“…Standardized reporting guidelines have been established within other disease processes and have been shown to improve patient outcomes [11,12]. The ENiGMA collaborators sought to standardize reporting in CAF research by establishing a list of core descriptors for CAF through an international Delphi technique [13]. These descriptors could be used standardize population description so that conclusions and treatments could be more easily translated to disease classification and clinical practice.…”

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confidence: 99%

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The use of core descriptors from the ENiGMA code study in recent literature: a systematic review

Khan,

Arline,

Williams

et al. 2024

Colorectal Disease

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AimThe heterogeneity in data quality presented in studies regarding Crohn's anal fistula (CAF) limit extrapolation into clinical practice. The ENiGMA collaborators established a core descriptor set to standardize reporting of CAF. The aim of this work was to quantify the use of these descriptors in recent literature.MethodWe completed a systematic review of PubMed and the Cochrane Library, extracting publications from the past 10 years specific to the clinical interventions and outcomes of CAF, and reported in line with PRISMA guidance. Each article was assessed for inclusion of ENiGMA descriptors. The median number of descriptors per publication was evaluated along with the overall frequency of each individual descriptor. Use of ENiGMA descriptors was compared between medical and procedural publications.ResultsNinety publications were included. The median number of descriptors was 15 of 37; 16 descriptors were used in over half of the publications while 17 were used in fewer than a third. Descriptors were more frequently used in procedural (n = 16) than medical publications (n = 14) (p = 0.031). In procedural publications, eight descriptors were more frequently used including Faecal incontinence, Number of previous fistula interventions, Presence and severity of anorectal stenosis and Current proctitis. Medical publications were more likely to include Previous response to biological therapy and Duration and type of current course of biological therapy.ConclusionWith many descriptors being used infrequently and variations between medical and procedural literature, the colorectal community should assess the need for all 37 descriptors.

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Section: Re Sultsmentioning

confidence: 99%

mentioning

confidence: 99%

The use of core descriptors from the ENiGMA code study in recent literature: a systematic review

Khan,

Arline,

Williams

et al. 2024

Colorectal Disease

View full text Add to dashboard Cite

show abstract

“…This is an area where Core Descriptor Sets can potentially be of use. Few such sets exist currently but this issue of Colorectal Disease contains one of the first, developed for Crohn's anal fistula [2]. What is perhaps most important about this is not the elements related to anal fistula in Crohn's disease per se, more that it is an exemplar of a methodology that should be more widely used for other conditions.…”

mentioning

confidence: 99%