Development of a high resolution gamma camera system using finely grooved GAGG scintillator

Yamamoto, Seiichi; Kataoka, J.; Oshima, T.; Ogata, Yoshiro; Watabe, Tadashi; Ikeda, Hayato; Kanai, Yasukazu; Hatazawa, Jun

doi:10.1016/j.nima.2016.03.060

Cited by 22 publications

(26 citation statements)

References 12 publications

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“…We successfully imaged the distribution of bremsstrahlung x-rays from C-14 using our developed LaGPS radiation imaging system. Its intrinsic spatial resolution for bremsstrahlung x-rays from C-14 was less than 1 mm FWHM, which is high enough for small animal imaging because the spatial resolution was almost as high as the previously reported gamma cameras for the higher energy gamma photons of Co-57 (122 keV) [22][23][24][25]. Since the hole separation of the parallel hole collimator was 1.2 mm, it determined the system spatial resolution, which is double the hole separation in the worst position.…”

Section: Discussionmentioning

confidence: 80%

Possibility analysis of bremsstrahlung x-ray imaging of C-14 radionuclide using a LaGPS radiation imaging system

Yamamoto

Nakanishi

Furukawa

et al. 2019

Biomed. Phys. Eng. Express

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The in-vivo imaging of C-14 is thought to be impossible because it is a pure beta-emitting radionuclide and the energy of beta particles is low. However, beta particles emit bremsstrahlung x-rays in subjects that may be imaged from the outside subjects. Thus, we imaged bremsstrahlung x-rays from a C-14 solution using a high resolution Ce-doped (Gd, La) 2 Si 2 O 7 (LaGPS) radiation imaging system. With a LaGPS radiation imaging system, we conducted bremsstrahlung x-ray imaging from a C-14 solution in a plastic container with 37 MBq radioactivity with and without a parallel hole collimator. Without it, images were obtained with a spatial resolution of ∼1 mm FWHM in less than 1 min of acquisition time. The energy spectrum of the bremsstrahlung x-rays from a C-14 solution showed a broad distribution with an average energy of ∼30 keV. With a parallel hole collimator, images of the C-14 solutions were also possible although the detected counts decreased to 2.4% of those without a collimator. The measured sensitivities of the LaGPS imaging system without and with a collimator for bremsstrahlung x-rays from C-14 solutions in a plastic container were 3.5×10 −5 and 8.5×10 −7 , respectively. We conclude that the imaging of bremsstrahlung x-rays from C-14 might be a new method for the in-vivo distribution imaging of small animals or plants.

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Section: Discussionmentioning

confidence: 80%

Possibility analysis of bremsstrahlung x-ray imaging of C-14 radionuclide using a LaGPS radiation imaging system

Yamamoto

Nakanishi

Furukawa

et al. 2019

Biomed. Phys. Eng. Express

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“…The size of the LaGPS plate was 35 mm × 35 mm × 1 mm thick. We slotted the LaGPS plate into 0.2 mm × 0.2-mm pixels using a dicing method [17]. The pixelated LaGPS plate had 0.2-mm pixels separated by air gaps with widths of 0.1 mm.…”

Section: Lagps Radiation Imaging Systemmentioning

confidence: 99%

Imaging of bremsstrahlung X-rays from tritium water in a plastic bag using a LaGPS radiation imaging system

et al. 2020

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A: Tritium (H-3) is a pure beta-emitting radionuclide and beta particles have extremely low energy (maximum energy: 18.6 keV). Thus the in-vivo imaging of H-3 is thought to be impossible. However, beta particles emit bremsstrahlung X-rays in subjects that may be imaged from outside of the subjects. We tried to image the bremsstrahlung X-rays from H-3 water using a newly developed radiation imaging system. The developed imaging system used a pixelated Ce-doped (Gd, La) 2 Si 2 O 7 (LaGPS) scintillator plate optically coupled to a flat-panel position-sensitive photomultiplier tube (FP-PMT). Using the imaging system, we conducted bremsstrahlung X-ray imaging from H-3 water in a plastic bag with 37-MBq radioactivity. We obtained tungsten slit mask images with a spatial resolution of ~3 mm full width at half maximum (FWHM). The energy spectrum of the bremsstrahlung X-rays from the H-3 water showed a broad distribution with an average energy of ~10 keV. The measured sensitivities of the LaGPS imaging system for bremsstrahlung X-rays from H-3 water in a plastic bag were 1.8 × 10 −7 . We conclude that the imaging of bremsstrahlung X-rays from H-3 water was really possible and it has a potential to be a new method for the in-vivo H-3 imaging of small animals, plants, or materials.

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“…Furthermore, Gd 3 Al 2 Ga 3 O 12 (GAGG) is one of the garnettype oxides which has a high density (6.63 g cm −3 ) and a large Z eff (54). There are a lot of studies on Ce 3+ -doped GAGG scintillators due to its high LY and fast decay time, [30][31][32][33][34][35][36][37][38] and this scintillator is in practical use. However, there are relatively few studies on scintillation properties of other rare-Earth-ions-doped GAGG.…”

Section: Introductionmentioning

confidence: 99%

Dopant concentration dependence on optical and scintillation properties of Eu-doped Gd₃Al₂Ga₃O₁₂ single crystals

Kunikata,

Watanabe,

Kantuptim

et al. 2023

Jpn. J. Appl. Phys.

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We have studied scintillation properties of Eu3+-doped Gd3Al2Ga3O12 single crystals. Gd3Al2Ga3O12 single crystals with different concentrations of Eu3+ (0.5, 1.0, 5.0, 10.0, and 15.0 %) were grown using the floating-zone method. In photoluminescence (PL) and scintillation properties, the Eu-doped Gd3Al2Ga3O12 single crystals showed emission peaks and several millisecond decay times due to 4f-4f transitions of Eu3+ ions. Pulse height spectra of all the samples were investigated under γ-ray irradiation from 137Cs (662 keV). The 0.5, 1.0, 5.0, and 10.0 % Eu-doped samples showed full energy peaks. Among all the samples, the 5.0 % Eu-doped Gd3Al2Ga3O12 single crystal showed the highest light yield of 36,000 photons/MeV.

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Development of a high resolution gamma camera system using finely grooved GAGG scintillator

Cited by 22 publications

References 12 publications

Possibility analysis of bremsstrahlung x-ray imaging of C-14 radionuclide using a LaGPS radiation imaging system

Possibility analysis of bremsstrahlung x-ray imaging of C-14 radionuclide using a LaGPS radiation imaging system

Imaging of bremsstrahlung X-rays from tritium water in a plastic bag using a LaGPS radiation imaging system

Dopant concentration dependence on optical and scintillation properties of Eu-doped Gd₃Al₂Ga₃O₁₂ single crystals

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Development of a high resolution gamma camera system using finely grooved GAGG scintillator

Cited by 22 publications

References 12 publications

Possibility analysis of bremsstrahlung x-ray imaging of C-14 radionuclide using a LaGPS radiation imaging system

Possibility analysis of bremsstrahlung x-ray imaging of C-14 radionuclide using a LaGPS radiation imaging system

Imaging of bremsstrahlung X-rays from tritium water in a plastic bag using a LaGPS radiation imaging system

Dopant concentration dependence on optical and scintillation properties of Eu-doped Gd3Al2Ga3O12 single crystals

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Dopant concentration dependence on optical and scintillation properties of Eu-doped Gd₃Al₂Ga₃O₁₂ single crystals