Development of a low cost microfluidic sensor for the direct determination of nitrate using chromotropic acid in natural waters

Cogan, Deirdre; Fay, Cormac; Boyle, David; Osborne, Conor; Kent, Nigel; Cleary, John; Diamond, Dermot

doi:10.1039/c5ay01357g

Cited by 36 publications

(21 citation statements)

References 18 publications

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“…Various techniques, such as colorimetry [22][23][24][25][26][27][28][29][30][31][32][33][34], chemiluminescence [35,36], fluorimetry [37][38][39][40], electrochemistry [41][42][43], and chromatography [44][45][46], have been proposed for nutrient determination. Among them, the colorimetric method using chromogenic agents is one of the most favored detection approaches due to its stability, excellent detection limits, simplicity, high cost efficiency, and analytical feasibility.…”

Section: Nutrientsmentioning

confidence: 99%

“…Among various colorimetric assay chemistries, the Griess assay method has been the mainstay for nitrite analysis for over a century [22][23][24][25][26][27][28][29][30][31][32][33][34]. The mechanism of the Griess assay method is that under acidic conditions, nitrite reacts with sulfanilic acid to produce a diazonium salt, which is then coupled to N-(1-naphthyl) ethylenediamine (NED), resulting in pink azo compounds that can be detected at 543 nm.…”

Section: Nitrate and Nitritementioning

confidence: 99%

“…Cogan et al developed a highly integrated system for nitrate determination. The system was based on the direct and simplified chromotropic acid reagent method, which eliminates the reduction step of nitrate to nitrite [30], as shown in Figure 2. The principle is that the chromotropic acid reacts with nitrate ions in a sulphuric acid medium, resulting in yellow products that can be detected at 430 nm.…”

Section: Nitrate and Nitritementioning

confidence: 99%

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Autonomous and In Situ Ocean Environmental Monitoring on Optofluidic Platform

et al. 2020

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Determining the distributions and variations of chemical elements in oceans has significant meanings for understanding the biogeochemical cycles, evaluating seawater pollution, and forecasting the occurrence of marine disasters. The primary chemical parameters of ocean monitoring include nutrients, pH, dissolved oxygen (DO), and heavy metals. At present, ocean monitoring mainly relies on laboratory analysis, which is hindered in applications due to its large size, high power consumption, and low representative and time-sensitive detection results. By integrating photonics and microfluidics into one chip, optofluidics brings new opportunities to develop portable microsystems for ocean monitoring. Optofluidic platforms have advantages in respect of size, cost, timeliness, and parallel processing of samples compared with traditional instruments. This review describes the applications of optofluidic platforms on autonomous and in situ ocean environmental monitoring, with an emphasis on their principles, sensing properties, advantages, and disadvantages. Predictably, autonomous and in situ systems based on optofluidic platforms will have important applications in ocean environmental monitoring.

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Section: Nutrientsmentioning

confidence: 99%

Section: Nitrate and Nitritementioning

confidence: 99%

Section: Nitrate and Nitritementioning

confidence: 99%

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Autonomous and In Situ Ocean Environmental Monitoring on Optofluidic Platform

et al. 2020

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“…Ketos focuses on real time, automated and smartconnected monitoring of water quantity and quality. Research in this area is The Future of Water 50 getting to the point that many of the key contaminants of interest can be sensed in real time and in-pipe, and the information can be transmitted to central servers for processing and response (Besmer et al, 2016;Cogan et al, 2015;Lambrou, Anastasiou, Panayiotou, & Polycarpou, 2014;Lin, Li, & Burns, 2017;Maity et al, 2017;Shahat et al, 2015;J. P R Sorensen et al, 2015; James P.R.…”

Section: Smart Decentralized Networkmentioning

confidence: 99%

The Future of Water: A Collection of Essays on “Disruptive” Technologies that may Transform the Water Sector in the Next 10 Years

Daigger¹,

Voutchkov²,

Lall³

et al. 2019

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work is licensed under a Creative Commons IGO 3.0 Attribution-NonCommercial-NoDerivatives (CC-IGO BY-NC-ND 3.0 IGO) license (http://creativecommons.org/licenses/by-nc-nd/3.0/igo/ legalcode) and may be reproduced with attribution to the IDB and for any non-commercial purpose. No derivative work is allowed.Any dispute related to the use of the works of the IDB that cannot be settled amicably shall be submitted to arbitration pursuant to the UNCITRAL rules. The use of the IDB's name for any purpose other than for attribution, and the use of IDB's logo shall be subject to a separate written license agreement between the IDB and the user and is not authorized as part of this CC-IGO license.

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“…The detection of nitrite in samples of different origins such as natural waters, processed meats, and biological samples like urine and blood plasma has been carried out by different research groups [11,12,13,14,15,16,17]. The ion could be detected by the three key instrumental methods, namely ion chromatography, electrochemistry (both potentiometry and voltammetry), and spectrometry.…”

Section: Introductionmentioning

confidence: 99%

Lab on a Chip for the Colorimetric Determination of Nitrite in Processed Meat Products in the Jordanian Market

et al. 2019

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Nitrite and Nitrate have been used extensively as additives in various meat products to enhance flavor, color, and to preserve the meat from the bacterial growth. High concentrations of nitrite can threat human health since several studies in the literature claim that nitrite is associated with cancer incidences, leukemia, and brain tumors. Therefore, it is vital to measure the nitrite concentrations in processed meat products. In this study, an in-lab miniaturized photometric detection system is fabricated to inspect the nitrite concentration in processed meat products in Jordan. The analytical performance of nitrite detection is evaluated based on three key statistical parameters; linearity, limit of detection, and limit of quantitation. Respectively, for the fabricated system, the three values are found to be equal to 0.995, 1.24 × 10−2 ppm, and 4.12 × 10−2 ppm. Adherence to Beer’s law is found over the investigated range from 2.63 ppm to 96.0 ppm. The developed system is utilized for photometric detection of nitrite in processed meat products available in the Jordanian market like pastrami, salami, and corned beef. In all of the analyzed samples, the nitrite content is found to be lower than 150 ppm, which represents the maximum allowable nitrite limit.

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Development of a low cost microfluidic sensor for the direct determination of nitrate using chromotropic acid in natural waters

Abstract: This study has demonstrated, for the first time, a microfluidic autonomous analyser for the direct determination of nitrate, incorporating a modified version of the chromotropic method resulting in a direct, quick, inexpensive and simple procedure to measure nitrate in situ.

Cited by 36 publications

References 18 publications

Autonomous and In Situ Ocean Environmental Monitoring on Optofluidic Platform

Autonomous and In Situ Ocean Environmental Monitoring on Optofluidic Platform

The Future of Water: A Collection of Essays on “Disruptive” Technologies that may Transform the Water Sector in the Next 10 Years

Lab on a Chip for the Colorimetric Determination of Nitrite in Processed Meat Products in the Jordanian Market

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