Development of a Method for Regioisomer Impurity Detection and Quantitation within the Raw Material 3-Chloro-5-Fluorophenol by Gas Chromatography

Denton, Justin R.; Chen, Yun; Loughlin, Thomas

doi:10.4172/2157-7064.1000356

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“…Most of these impurities are controlled at the process level itself and the left over if any are eliminated further at consequent stages. Denton et al [1], explored the possibilities of detection and quantification of regioisomer impurities associated with 3-chloro-5-fluorophenol along with other related impurities using the entire gas chromatography area % method. The study discussed several other alternative strategies to control the impurities elated to 3-chloro-5-fluorophenol.…”

Section: Editor's Notementioning

confidence: 99%