Development of a Risk Score to Predict Sudden Infant Death Syndrome

Polavarapu, Mounika; Klonoff-Cohen, Hillary; Joshi, Divya; Kumar, Praveen; An, Ruopeng; Rosenblatt, Karin A.

doi:10.3390/ijerph191610270

Cited by 8 publications

(5 citation statements)

References 59 publications

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“…In a previous work, Matturri et al [33] reported from our series of 102 cases that males were 62.74% versus 37.26% for females. The male sex has been considered to be a risk factor for SIDS along with prone position, death during sleep, co-sleeping, and preterm birth, among others [34,35].…”

Section: Subjects' Characteristicsmentioning

confidence: 99%

Autopsy for Medical Diagnostics: Finding the Cause of Sudden Unexpected Death through Investigation of the Cardiac Conduction System by Serial Sections

Ottaviani

Ramos

2023

Diagnostics

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Sudden unexpected death (SUD) is a fatal event that occurs in an apparently healthy subject in a way that such an abrupt outcome could have not been predicted. SUD—including sudden intrauterine unexplained death (SIUD), sudden neonatal unexpected death (SNUD), sudden infant death syndrome (SIDS), sudden unexpected death of the young (SUDY), and sudden unexpected death in the adult (SUDA)—occurs as the first manifestation of an unknown underlying disease or within a few hours of the presentation of a disease. SUD is a major unsolved, shocking form of death that occurs frequently and can happen at any time without warning. For each case of SUD, a review of clinical history data and performance of a complete autopsy, particularly focused on the study of the cardiac conduction system, were carried out according to the necropsy protocol devised by the Lino Rossi Research Center, Università degli Studi di Milano, Italy. Research cases collected and selected for this study were represented by 75 SUD victims that were subdivided into 15 SIUD, 15 SNUD, 15 SUDY, and 15 SUDA victims. After a routine autopsy and clinical history analysis, death remained unexplained, and hence a diagnosis of SUD was assigned to 75 subjects, which included 45 females (60%) and 30 (40%) males ranging in age from 27 gestational weeks to 76 years. Serial sections of the cardiac conduction system disclosed frequent congenital alterations of the cardiac conduction system in fetuses and infants. An age-related significant difference in distribution among the five age-related groups was detected for the following anomalies of the conduction system: central fibrous body (CFB) islands of conduction tissue, fetal dispersion, resorptive degeneration, Mahaim fiber, CFB cartilaginous meta-hyperplasia, His bundle septation, sino-atrial node (SAN) artery fibromuscular thickening, atrio-ventricular junction hypoplasia, intramural right bundle branch, and SAN hypoplasia. The results are useful for understanding the cause of death for all SUD cases that were unexpected and would have otherwise remained unexplained, so as to motivate medical examiners and pathologists to perform more in-depth studies.

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Section: Subjects' Characteristicsmentioning

confidence: 99%

Autopsy for Medical Diagnostics: Finding the Cause of Sudden Unexpected Death through Investigation of the Cardiac Conduction System by Serial Sections

Ottaviani

Ramos

2023

Diagnostics

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“…Jedną z głównych teorii dotyczących przyczyn występowania SIDS jest hipoteza potrójnego ryzyka, zgodnie z którą zespół nagłej śmierci łóżeczkowej występuje w przypadku nakładania się czynników ryzyka dotyczących zarówno osoby dziecka, jego okresu rozwoju, a także czynników środowiskowych [6][24] [26]. Wspomniany trójskładnikowy model, zaliczany do głównych teorii, objaśniających złożoność i wieloaspektowość źródeł występowania SIDS, zakłada, że nagła śmierć na skutek SIDS może wystąpić u dziecka z osobniczą podatnością (np.…”

Section: Wstępunclassified

“…predyspozycją genetyczną, nieprawidłowością pnia mózgu) pod wpływem czynnika wyzwalającego (dym tytoniowy, niedrożność dróg oddechowych) w krytycznym momencie rozwoju (zarówno układu nerwowego jak i krążenia czy oddechowego). Zgodnie z tą teorią niemowlę umrze na skutek SIDS tylko w wypadku łącznego zaistnienia wszystkich trzech czynników [14]. Do głównych zadań stawianych przed medycyną w chwili obecnej należy zatem propagowanie i rozpowszechnianie wiedzy na temat ustalonych czynników ryzyka wystąpienia zespołu nagłej śmierci łóżeczkowej, wśród osób sprawujących opiekę nad niemowlętami w wieku, w którym wystąpienie omawianego zjawiska u dziecka jest najbardziej prawdopodobne [3].…”

Section: Wstępunclassified

“…Szacuje się, że unikanie palenia podczas ciąży może zmniejszyć liczbę przypadków SIDS o prawie 21 procent [35]. Kobiety w okresie ciąży powinny być zatem przekonywane, aby rzuciły palenie, a także chroniły dziecko po urodzeniu od kontaktu z dymem papierosowym, pochodzącym z otoczenia [6].…”

Section: Czynniki Ryzyka Wystąpienia Sids Związane Z Używaniem Substa...unclassified

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Sudden infant death syndrome (SIDS) - How to reduce the risk?

Dengler

Wolanin

Stawikowski

et al. 2023

J Educ Health Sport

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Sudden infant death syndrome (SIDS) is a complex, multifactorial phenomenon with an etiology that has not been fully clarified to this day. Despite a noticeable decrease in the number of SIDS cases worldwide, sudden infant death syndrome remains one of the most common causes of death among children in infancy. Sudden infant death syndrome is still the subject of scientific research aimed to clearly determine and identify potential pathogenetic factors responsible for the occurrence of SIDS. Many years of efforts to clarify the etiology of the discussed issue have made it possible to characterize important factors that increase the risk of sudden infant death syndrome. In addition, research has made it possible to develop important approaches that make a significant contribution to reduce the risk of SIDS in an infant. Complete knowledge of the specific conditions that have a protective effect against SIDS will significantly reduce the risk of sudden infant death syndrome, so a very important aspect is not only their precise analysis, but also their propagation among the public.

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“…Anah tar Ke li me ler: Ani bebek ölümü sendromu; anneler; farkındalık; risk faktörleri Some of these factors are prone or side-lying position, using the same bed with the baby, sleeping on a soft surface, excessive heat, smoking of the mother during pregnancy, and late or no prenatal care. [4][5][6][7] The World Health Organization states that more than half of the deaths of children under the age of five are in preventable conditions. It has been reported that almost a quarter of these deaths are in infants who die within their first year of life.…”

mentioning

confidence: 99%

Maternal Awareness in the Risk Factors Attributed to Sudden Infant Death Syndrome: Descriptive Study

BORAN,

KAHRİMAN

2023

Turkiye Klinikleri J Foren Sci Leg Med

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Sudden infant death syndrome (SIDS) is expressed as the unexpected and unexplained sudden death of infants under the age of one after a detailed investigation, clinical history, and autopsy examina-tion. 1,2 SIDS, which is associated with sleep, is also defined as sudden crib death or cot death. 3 Although the etiology of SIDS cannot be fully explained, it is thought that many factors may cause this condition.

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Development of a Risk Score to Predict Sudden Infant Death Syndrome

Cited by 8 publications

References 59 publications

Autopsy for Medical Diagnostics: Finding the Cause of Sudden Unexpected Death through Investigation of the Cardiac Conduction System by Serial Sections

Autopsy for Medical Diagnostics: Finding the Cause of Sudden Unexpected Death through Investigation of the Cardiac Conduction System by Serial Sections

Sudden infant death syndrome (SIDS) - How to reduce the risk?

Maternal Awareness in the Risk Factors Attributed to Sudden Infant Death Syndrome: Descriptive Study

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