Development of a risk stratification system for the occurrence of prolonged postoperative ileus after colorectal surgery: A prospective risk factor analysis

Vather, Ryash; Josephson, Rachel; Jaung, Rebekah; Robertson, Jason; Bissett, Ian P.

doi:10.1016/j.surg.2014.12.005

Cited by 133 publications

(162 citation statements)

References 21 publications

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“…The usefulness of the absorptive anti-adhesion barrier film Seprafilm [9][10][11][12][13][14] has been shown by many randomized control studies and meta-analysis, although studies with negative results do exist [15][16][17][18] . Interestingly, the reports on peritoneal adhesion or BO associated with laparoscopic surgery, the use of which has rapidly spread in recent years, are few compared with reports on open surgery 11,[19][20][21][22][23] . However, one report noted a lack of reduction in BO with laparoscopic surgery 24) .…”

Section: Introductionmentioning

confidence: 99%

Absorptive anti-adhesion barrier for the prevention of bowel obstruction after laparoscopic colorectal cancer surgery

Fujii

Tsukamoto

Shimada

et al. 2018

J Anus Rectum Colon

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Abstract:Objectives: The protective efficacy of an absorptive adhesion prevention product (Seprafilm ) against bowel obstruction (BO) during open surgery was demonstrated in a large-scale randomized controlled clinical trial in Europe and America. However, the efficacy of Seprafilm against BO in laparoscopic surgery remains uncertain. The objective of this study was to clarify the protective efficacy of Seprafilm against BO after laparoscopic surgery for colorectal cancer. Methods: From 2009 to 2016, 1328 laparoscopic colorectal resections were performed for colorectal cancer. From 2009, Seprafilm was used for preventing BO in laparoscopic colorectal surgery. The incidence of BO and short-term results were compared between the Seprafilm and non-Seprafilm groups after propensity score matching. Results: Propensity scoring generated 270 matched patients per group for the comparisons between the Seprafilm and non-Seprafilm groups. The two groups showed no significant differences regarding patients' backgrounds. Among all patients, 73.1% (19/26) of BO occurred within 30 days after the surgery. Significantly lower incidences of all grade (2.6% vs. 7.0%; p = 0.016) and grade 2 + 3a (1.5% vs. 5.2%; p = 0.017) BO were observed in the Seprafilm group than in the non-Seprafilm group; no significant difference regarding grade 3b BO (1.1% vs. 1.9%; p = 0.476) was found. A significant difference in BO within 30 days was also noted between the two groups (1.9% vs. 5.2%, p = 0.036). There were no significant differences between the groups regarding anastomotic leakage and deep surgical site infection. Conclusions: Seprafilm was useful for preventing BO, requiring decompression therapy of the bowel, after laparoscopic colorectal surgery without increasing adverse events.

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Section: Introductionmentioning

confidence: 99%

Absorptive anti-adhesion barrier for the prevention of bowel obstruction after laparoscopic colorectal cancer surgery

Fujii

Tsukamoto

Shimada

et al. 2018

J Anus Rectum Colon

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“…Study design: 10 were single‐centerd, whereas only 1 study was conducted as a multicenter trial; 2 were endorsed recommendations; and 1 was a letter of response to an original article …”

Section: Resultsmentioning

confidence: 99%

Gastrointestinal Dysfunction in Critical Illness: A Review of Scoring Tools

Asrani

Brown

Huang

et al. 2019

J Parenter Enteral Nutr

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Gastrointestinal dysfunction/failure (GDF) is a common feature of critical illness. There is no consensus on the best way to measure severity of GDF. The aim of this systematic review was to evaluate and compare all gastrointestinal dysfunction scoring tools (GDSTs) to determine aspects that might be useful to construct a new gut scoring tool for intensive care patients. A comprehensive database search of MEDLINE and EMBASE on GDSTs in acute, surgical, and critically ill patients was conducted. Extraction of data was conducted for study characteristics, GDST domains, feasibility of the scoring process, clinical outcomes, and quality of life attributes; independent authors conducted the search, applied the selection criteria, and extracted the data. Methodological quality of studies was assessed. A GDST matrix was created using 14 scoring tools and was evaluated for validity. The 14 GDSTs identified were used in different clinical settings, including critical illness, acute intestinal failure, gastrointestinal disorders, and postoperative patients. There was marked variation between these GDSTs. There is a lack of emphasis in the use of objective laboratory parameters and gut‐specific biomarkers to measure GDF in majority of the studies. The overall quality of evidence was poor, and most tools lacked formal validation. This review has highlighted the lack of an agreed and validated approach to scoring GDF in critical illness. The identified aspects of GDF relevant to critical illness should now be incorporated in a new scoring tool and prospectively tested in intensive care patients.

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“…The operating time in the DKT group was approximately 30 min shorter than that in the placebo group. Although the operating time itself was not an independent risk factor for postoperative paralytic ileus [38], it may have a potentially negative effect on bowel recovery [39].…”

Section: Discussionmentioning

confidence: 95%

Clinical pharmacology of daikenchuto assessed by transit analysis using radiopaque markers in patients with colon cancer undergoing open surgery: a multicenter double-blind randomized placebo-controlled study (JFMC39-0902 additional study)

et al. 2015

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Development of a risk stratification system for the occurrence of prolonged postoperative ileus after colorectal surgery: A prospective risk factor analysis

Cited by 133 publications

References 21 publications

Absorptive anti-adhesion barrier for the prevention of bowel obstruction after laparoscopic colorectal cancer surgery

Absorptive anti-adhesion barrier for the prevention of bowel obstruction after laparoscopic colorectal cancer surgery

Gastrointestinal Dysfunction in Critical Illness: A Review of Scoring Tools

Clinical pharmacology of daikenchuto assessed by transit analysis using radiopaque markers in patients with colon cancer undergoing open surgery: a multicenter double-blind randomized placebo-controlled study (JFMC39-0902 additional study)

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