Development of a severity scoring system for acute haemorrhage in anaesthetized domestic cats: the CABSS score

Zeiler, Gareth Edward; Fuller, Andrea; Rioja, Eva; Kamerman, Peter R.; Buck, Roxanne K.; Pohlin, Friederike; Dzikiti, Brighton T.

doi:10.1016/j.vaa.2019.11.008

Cited by 5 publications

(8 citation statements)

References 26 publications

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“…Based on these anesthesia records, HR, MBP, systolic blood pressure (SBP), and airway pressure were measured just before the CT scan. In addition, the SI (SI=HR/SBP) was calculated [ 31 , 41 ].…”

Section: Methodsmentioning

confidence: 99%

“…The patients were classified into a low MBP group (MBP <60 mmHg just before the CT scan) and a normal MBP group (MBP≥60 mmHg just before the CT scan) [ 36 ]. They were also classified into a high SI group (SI ≥1.0) and a normal SI group (SI <1.0), indicating shock [ 31 , 41 ]. Patients were further classified into two groups according to the presence of hypoproteinemia, anemia, intra-abdominal mass, and cardiac disease.…”

Section: Methodsmentioning

confidence: 99%

“…Therefore, we hypothesized that the CVC size on CT examination under general anesthesia in dogs reflects circulatory dynamics and aimed to investigate factors affecting CVC size. Furthermore, we focused on low mean blood pressure (MBP) and high shock index (SI), which are indicators of hypovolemia [ 3 , 9 , 31 , 41 ]; hypoproteinemia and anemia [ 39 ], which are indicators of blood loss; intra-abdominal masses, which can increase intra-abdominal pressure [ 6 , 19 ]; cardiac disease [ 18 ]; and airway pressure [ 33 ], which can affect venous volume, as candidate factors affecting CVC size.…”

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confidence: 99%

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Evaluation of caudal vena cava size using computed tomography in dogs under general anesthesia

Hanazono

Nakamoto

Hori

et al. 2022

The Journal of Veterinary Medical Science

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This study investigated the association between caudal vena cava (CVC) size and circulatory dynamics in dogs using computed tomography (CT) under general anesthesia. The subjects were 104 dogs who had undergone CT under general anesthesia in the past. The ratio of short diameter of the CVC to aortic diameter (CVCS/Ao) and the ratio of long to short diameter of the CVC (CVCL/CVCS) in the thorax and abdomen, respectively, were calculated using factors such as mean blood pressure (MBP), shock index (SI), anemia, hypoproteinemia, presence of intra-abdominal mass, and cardiac disease. There was a significant but negligible negative correlation between CVCS/Ao and MBP. In contrast, no significant correlation was found between CVC size and SI. The low MBP group had significantly higher CVCS/Ao of the thorax than the normal MBP group. The group with intraabdominal mass had significantly lower CVCS/Ao of the abdomen than the group without intraabdominal mass. The group with cardiac disease had significantly lower CVCL/CVCS of the thorax 4 than the group without cardiac disease. In multiple regression analysis, low MBP, cardiac disease, intra-abdominal mass, and anemia were significant factors for CVCS/Ao of the thorax, CVCL/CVCS of the thorax, CVCS/Ao of the abdomen, and CVCL/CVCS of the abdomen, respectively. In conclusion, CVC size assessment using CT in dogs under general anesthesia is influenced by various factors.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

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Evaluation of caudal vena cava size using computed tomography in dogs under general anesthesia

Hanazono

Nakamoto

Hori

et al. 2022

The Journal of Veterinary Medical Science

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“…Furthermore, at T0, all cats had normal HCT and Hb concentrations before the start of each experiment. In a study by Zeiler et al (2020), healthy cats were anaesthetised with buprenorphine, alfaxalone, and isoflurane, and controlled blood loss was generated (4.5 ± 1.1 mL/kg of blood), resulting in a mean HCT reduction of 0.00 (±0.01) L/L or −1.8 (±3.1)% and a mean Hb reduction of 3 (±2) mg/dL or −3.2 (±2.5)% [85]. The amount of blood collected from the cats in our study did not interfere with HCT and Hb concentrations.…”

Section: Haematocrit and Haemoglobinmentioning

confidence: 99%

The Effect of a Subsequent Dose of Dexmedetomidine or Other Sedatives following an Initial Dose of Dexmedetomidine on Electrolytes, Acid–Base Balance, Creatinine, Glucose, and Cardiac Troponin I in Cats: Part II

Margeti,

Kazakos,

Galatos

et al. 2024

Veterinary Sciences

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The administered dose of dexmedetomidine may occasionally fail to produce the anticipated sedative effects. Therefore, a subsequent dose or administration of another sedative may enhance sedation; however, patient safety may be affected. The safety of seven different drugs administered at the following time point after an insufficient dose of dexmedetomidine was evaluated in a crossover, blind, experimental study that included six healthy adult cats. All cats received an initial dose of dexmedetomidine and a subsequent dose of either dexmedetomidine (Group DD), NS 0.9% (DC), tramadol (DT), butorphanol (DBT), buprenorphine (DBP), ketamine (DK), or midazolam (DM). Animal safety was assessed using repeated blood gas analysis and measurement of electrolytes, glucose, cardiac troponin I, and creatinine to evaluate cardiac, respiratory, and renal function. The median values of creatinine, cardiac troponin I, pH, partial pressure of carbon dioxide, potassium, and sodium did not change significantly throughout the study. Heart rate was significantly decreased in all groups after administration of the drug combinations, except for in the DK group. Respiratory rate decreased significantly after administration of the initial dose of dexmedetomidine and in the DBP and DM groups. The partial pressure of oxygen, although normal, decreased significantly after the administration of dexmedetomidine, whereas the median concentration of glucose increased significantly following the administration of dexmedetomidine. The results of our study suggest that the drug combinations used did not alter the blood parameters above normal limits, while cardiac and renal function were not compromised. Therefore, a safe level of sedation was achieved. However, the administration of dexmedetomidine reduced the partial pressure of oxygen; thus, oxygen supplementation during sedation may be advantageous. Additionally, the increase in glucose concentration indicates that dexmedetomidine should not be used in cats with hyperglycaemia, whereas the decrease in haematocrit suggests that dexmedetomidine is not recommended in anaemic cats.

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“…This study was part of a larger fluid resuscitation project and only data relevant to the present study are reported. The sample size was based on availability of cats from the research colony and the study budget, as previously described (Zeiler et al 2020). The cats were housed in a communal indooreoutdoor cattery.…”

Section: Animalsmentioning

confidence: 99%

Investigation of biomarkers for impending fluid overload in a feline acute haemorrhage-resuscitation model

Zeiler

Dzikiti

Kamerman

et al. 2021

Veterinary Anaesthesia and Analgesia

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Development of a severity scoring system for acute haemorrhage in anaesthetized domestic cats: the CABSS score

Cited by 5 publications

References 26 publications

Evaluation of caudal vena cava size using computed tomography in dogs under general anesthesia

Evaluation of caudal vena cava size using computed tomography in dogs under general anesthesia

The Effect of a Subsequent Dose of Dexmedetomidine or Other Sedatives following an Initial Dose of Dexmedetomidine on Electrolytes, Acid–Base Balance, Creatinine, Glucose, and Cardiac Troponin I in Cats: Part II

Investigation of biomarkers for impending fluid overload in a feline acute haemorrhage-resuscitation model

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