Development of a tandem-electrostatic-quadrupole accelerator facility for BNCT

Kreiner, Andrés J.; Vento, V.; Levinas, P.; Bergueiro, J.; Paolo, H. Di; Burlón, A. A.; Kesque, J.M.; Valda, A.A.; Debray, M. E.; Somacal, H.; Minsky, D.M.; Estrada, Luis Alfonso; Hazarabedian, A.; Johann, F.; Sandin, J.C. Suarez; Castell, W.; Davidson, J.; Davidson, M.; Giboudot, Y.; Repetto, M.; Obligado, Martín; Nery, J.P.; Huck, H.; Igarzábal, M.; Salares, A. Fernandez

doi:10.1016/j.apradiso.2009.03.084

Cited by 12 publications

(10 citation statements)

References 5 publications

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“…The TESQ accelerator general layout has already been discussed in previous publications [5][6][7]. The accelerating column consists of a series of stacked cylindrical boxes which are separated by 200kV and 40cm air gaps (a total of 7 to reach 1.2MV, the first one being at ground potential).…”

Section: Methodsmentioning

confidence: 99%

“…Accelerators offer a number of major advantages over reactor-based sources for clinical applications. In particular the neutron energy spectrum from certain nuclear reactions is much softer than the one coming from fission, which makes it easier to generate the "ideal" epithermal neutron spectrum (needed to treat a deep seated tumor), and hence the quality of the neutron field can be designed to exceed the quality of the neutron field for reactor-based neutron sources [2,[5][6][7].…”

Section: Introductionmentioning

confidence: 99%

“…We shall discuss and highlight in this paper the present status of an ongoing project to develop a folded Tandem-Electrostatic-Quadrupole (TESQ) accelerator facility for Accelerator-Based Boron Neutron Capture Therapy (AB-BNCT) at the Atomic Energy Commission of Argentina (CNEA) [5][6][7] based on the 7 Li(p,n) 7 Be reaction, slightly beyond its resonance, at 2.3MeV. The machine being designed and constructed is a folded TESQ with a terminal at 1.2MV intended to work in air, to avoid the need for a pressure vessel and for an insulating gas installation.…”

Section: Introductionmentioning

confidence: 99%

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Hadron Therapy in Latin America

Bergueiro¹,

Burlón²,

Paolo³

et al. 2010

AIP Conference Proceedings

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The use of proton and heavy ion beams for radiotherapy is a well established cancer treatment modality in the first world, which is becoming increasingly widespread, due to its clear advantages over conventional photon-based treatments. This strategy is suitable when the tumor is spatially well localized. Also the use of neutrons has tradition. Here Boron Neutron Capture Therapy (BNCT) stands out, though on a much smaller scale, being a promising alternative for tumors which are diffuse and infiltrating. On this sector, so far only nuclear reactors have been used as neutron sources. In this paper we briefly describe the situation in Latin America and in particular we discuss the present status of an ongoing project to develop a folded Tandem-ElectroStatic-Quadrupole (TESQ) accelerator for Accelerator-Based (AB)-Boron Neutron Capture Therapy (BNCT) at the Atomic Energy Commission of Argentina. The project goal is a machine capable of delivering 30 mA of 2.4 MeV protons to be used in conjunction with a neutron production target based on the 7 Li(p,n) 7 Be reaction. These are the specifications needed to produce sufficiently intense and clean epithermal neutron beams to perform BNCT for deep-seated tumors in less than an hour. The machine being currently designed and constructed is a folded TESQ with a terminal at 0.6MV as a smaller scale prototype. Since the concept is modular the same structure will be used for the 1.2MV final accelerator.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Hadron Therapy in Latin America

Bergueiro¹,

Burlón²,

Paolo³

et al. 2010

AIP Conference Proceedings

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“…Among the projects of the first decade of the 21st century, the following should be noted. An elec trostatic quadrupole tandem accelerator to obtain a 2.5 MeV proton beam with a current of 20-30 mA [48,49] is being developed at the Institute of Science and Technology, San Martin (Argentina). The success of the project is rather probable, but the accelerator will be more suitable for research purposes than for the introduction of BNCT into clinical practice.…”

Section: Charged Particle Accelerators For Bnctmentioning

confidence: 99%

Accelerator based epithermal neutron source

Taskaev

2015

Phys. Part. Nuclei

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“…To heat superficial tumors many techniques have been proposed for noninvasive hyperthermia applicators [4][5]. For the better penetration of energy to deep located tumors low frequencies are utilized and for confinement of energy with high motion high frequencies are utilized [6].…”

Section: Introductionmentioning

confidence: 99%

A Two Slotted Circular Microwave Antenna Design for Hyperthermia System Applicators

Sethi¹,

Nijhawan²

2016

IJCA

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The critical element in the hyperthermia system is an antenna. The quality of the system and performance of antenna determines the electromagnetic energy (EM) deposition into the tissue. This paper presents the design and simulation of two slotted circular microwave based antenna used for hyperthermia applicator. The antenna is designed to operate at a frequency of 2.45GHz which is a designated medical band frequency to be used for hyperthermia applicators. The performance of the two slotted circular microwave antenna is compared with conventional circular microwave antenna. The result shows that slotted antenna offers better gain, high directivity, improved VSWR and an excellent return loss. The design of the proposed two slotted antenna can be used as a single antenna element in future for cancer specific deep region hyperthermia system.

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Development of a tandem-electrostatic-quadrupole accelerator facility for BNCT

Cited by 12 publications

References 5 publications

Hadron Therapy in Latin America

Hadron Therapy in Latin America

Accelerator based epithermal neutron source

A Two Slotted Circular Microwave Antenna Design for Hyperthermia System Applicators

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