Development of Anti-Wrinkle Cream From Pueraria Candollei Var. Mirifica (Airy Shaw and Suvat.) Niyomdham, “Kwao Krua Kao” for Menopausal Women

Abstract

Objective: The aim of this study was to incorporate Peraria candollei var. mirifica extract into the cream, to evaluate the physical properties and to conduct the skin tests in participants.Methods: Pueraria candollei var. mirifica was extracted with 95% ethanol to obtain crude pueraria extract (PCM). Crude PCM was developed as an anti-wrinkle PCM cream (B) intended for menopausal women. PCM cream was evaluated for stability of pH and viscosity, primary skin irritation, wrinkle reduction and moisturizing as well as customer satisfaction. Cream base (A) and cream purchased from the market (C) were used for comparison. ANOVA post hoc Turkey was used to analyze the variance (p0.05) of the mean comparisons between groups by cluster analysis. Results: The PCM cream appeared as white color, pH was 6.80, and viscosity was 4.069±0.01 Pa. s, as well as physical characteristic and texture, were acceptable and no irritating reaction. PCM cream exhibited a similar level of moisturizer as cream A and C. The PCM cream revealed an ability to decrease the wrinkle surface and wrinkle volume after applied for 7 and 14 d that shows the activity of this product performed from the PCM extract. Satisfaction of PCM cream showed good acceptance.Conclusion: These results suggest that PCM cream has the ability to reduce skin wrinkles. It is a good product for postmenopausal women and may also be of benefit for the general population for protection skin wrinkle.

Preparation and Stability Evaluation of Ll-37 Cream

“…Destabilization of the emulsion through hydrolysis occurred during storage at elevated temperatures [13]. These findings are in line with a previous study using an anti-wrinkle cream which demonstrated that higher temperatures resulted in increased viscosity [19]. As evidenced in this study, storing the emulsions at 4 °C, 28 °C, and 40 °C resulted in an acceptably stable pH at nearly 6.0, which is tolerable and gentle to the skin.…”

Botanical Biometrics: Exploring Morphological, Palynological, and DNA Barcoding Variations in White Kwao Krua (Pueraria candollei Grah. ex Benth. and P. mirifica Airy Shaw & Suvat.)

“…White Kwao Krua contains chromene compounds, such as deoxymiroestrol, miroestrol, and isomiroestrol, exhibiting a distinctive estrogen-like molecular structure, and isoflavonoids, namely genistein, daidzein, and puerarin [3,16]. Additionally, it is employed for breast augmentation and esthetic enhancement purposes [17]. Consequently, it is distributed through herbal markets, drugstores, and online retail platforms in various forms, including tablets, capsules, cookies, creams, and gels.…”

Activity of 96% Ethanol Extract of Chrysophyllum Cainito L. In Increasing Vertebrae Trabecular Osteoblast Cell Number in Male Mice

“…Phytoestrogens are a group of compounds derived from plants that have estrogen-like structures or can replace the function of estrogen in its bond either with estrogen receptors ([ERs]-dependent pathway) or not (ER-independent pathway) [7,8]. Besides being easy to obtain and having no side effects, the phytoestrogens are also reported to have activity for the treatment of estrogen deficiency [9][10][11], thereby providing an alternative treatment for potent osteoporosis [12].…”