Development of Bio-chemical Sensor System Integrated with Blood Extraction Device

Khumpuang, Sommawan; Fujioka, K.; Saito, Susumu

doi:10.1109/nems.2007.352150

Cited by 6 publications

(3 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… With excellent ability for minimally invasive health monitoring, especially for hollow microneedles, and taking advantage of pain-free, ease of use, minimal invasiveness, faster healing at injection site, and low risk of microbial penetration, microneedle-based chemical and biosensors have been rapidly developed as diagnostic tools for transdermal monitoring. Table summarizes the existing microneedle-based sensors and their applications in detecting different kinds of markers. − …”

Section: Chemical Sensors Integrated With Nature-inspired Structuresmentioning

confidence: 99%

Disease Detection with Molecular Biomarkers: From Chemistry of Body Fluids to Nature-Inspired Chemical Sensors

et al. 2019

View full text Add to dashboard Cite

This article aims to review nature-inspired chemical sensors for enabling fast, relatively inexpensive, and minimally (or non-) invasive diagnostics and follow-up of the health conditions. It can be achieved via monitoring of biomarkers and volatile biomarkers, that are excreted from one or combination of body fluids (breath, sweat, saliva, urine, seminal fluid, nipple aspirate fluid, tears, stool, blood, interstitial fluid, and cerebrospinal fluid). The first part of the review gives an updated compilation of the biomarkers linked with specific sickness and/or sampling origin. The other part of the review provides a didactic examination of the concepts and approaches related to the emerging chemistries, sensing materials, and transduction techniques used for biomarker-based medical evaluations. The strengths and pitfalls of each approach are discussed and criticized. Future perspective with relation to the information and communication era is presented and discussed.

show abstract

Section: Chemical Sensors Integrated With Nature-inspired Structuresmentioning

confidence: 99%

Disease Detection with Molecular Biomarkers: From Chemistry of Body Fluids to Nature-Inspired Chemical Sensors

et al. 2019

View full text Add to dashboard Cite

show abstract

“…Fig1 illustrates the pressure-gradient driven tank or vacuum tank which was used as a pumping source, covering rubber used for sealing the tank, puncturing needle for connecting the vacuum tank to the external liquid reservoir after a puncture. The vacuum tank is used for the drawing blood [2]. This paper proposes a novel mechanism to draw blood without external pump or vacuum tank, the deformation of PDMS(Polydimethylsiloxane) is used to achieve the purpose.…”

Section: Introductionmentioning

confidence: 99%

Design and Fabrication of Blood Drawing Device

Chien

2011

AMR

View full text Add to dashboard Cite

This paper proposed a novel device to draw blood from the finger. PDMS is used as an actuated pump, the device has an advantage in a precise controlled the volume of blood drawn. The operation process of the blood drawing device with the deflection of the PDMS membrane is to generate negative pressure. For measuring the performance of the device, we also fabricate a PDMS tank as pig’s skin. Two different viscosity fluid are used, the red ink and pig’s blood. The result of red ink drawn is 0.2cc, and the pig’s blood is 0.1cc.

show abstract

“…The therapeutic potential presented by microneedles for bypassing the skin's barrier function has inspired a great amount of research interest. To date, microneedles have been investigated for several skin related clinical applications, such as drug delivery 1–4, blood sampling 5, biopsy extraction 6, and light delivery 7. Microneedles avoid excessive mechanical damage to the healthy tissue while also mitigating blood loss, tissue disruption, and patient discomfort 8–10.…”

Section: Introductionmentioning

confidence: 99%