Development of botanical and fish oil standard reference materials for fatty acids

Schantz, Michele M.; Sander, Lane C.; Sharpless, Katherine E.; Wise, Stephen A.; Yen, James H.; NguyenPho, Agnes; Betz, Joseph M.

doi:10.1007/s00216-013-6747-y

Cited by 17 publications

(23 citation statements)

References 16 publications

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“…This material is part of a growing series of reference standards developed by NIST for the analysis of botanical dietary supplements and food ingredients [28–31]. SRM 3255 was developed to assist in the validation of new analytical methods for the determination of catechins and methylated xanthines in green tea extracts.…”

Section: Resultsmentioning

confidence: 99%

Orthogonal analytical methods for botanical standardization: Determination of green tea catechins by qNMR and LC–MS/MS

Napolitano

Gödecke

Lankin

et al. 2014

Journal of Pharmaceutical and Biomedical Analysis

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The development of analytical methods for parallel characterization of multiple phytoconstituents is essential to advance the quality control of herbal products. While chemical standardization is commonly carried out by targeted analysis using gas or liquid chromatography-based methods, more universal approaches based on quantitative 1H NMR (qHNMR) measurements are being used increasingly in the multi-targeted assessment of these complex mixtures. The present study describes the development of a 1D qHNMR-based method for simultaneous identification and quantification of green tea constituents. This approach utilizes computer-assisted 1H iterative Full Spin Analysis (HiFSA) and enables rapid profiling of seven catechins in commercial green tea extracts. The qHNMR results were cross-validated against quantitative profiles obtained with an orthogonal LC-MS/MS method. The relative strengths and weaknesses of both approaches are discussed, with special emphasis on the role of identical reference standards in qualitative and quantitative analyses.

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Section: Resultsmentioning

confidence: 99%

Orthogonal analytical methods for botanical standardization: Determination of green tea catechins by qNMR and LC–MS/MS

Napolitano

Gödecke

Lankin

et al. 2014

Journal of Pharmaceutical and Biomedical Analysis

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“…Numerous comparative studies have been conducted with different aims, e.g., to test different methods of analysis [38,39], to determine the suitability for application of one or more methods [40], to establish precision of the methods by determining their reproducibility limits and make recommendation for their use in laboratory practice [41,42], to evaluate and possibly improve analytical methods or laboratory performance, or to certify reference materials [43][44][45]. Due to the heterogeneity of FAs in animal fats, it is also necessary to study the extraction and derivatization procedure in order to obtain accurate quantitative and qualitative results [38].…”

Section: Introductionmentioning

confidence: 99%

Determination of the fatty acids in fish tissue and feed — comparison of different methods and statistical evaluation

Trbović

Polak

Demšar

et al. 2018

Acta Chromatographica

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With the aim to reinforce laboratory competence in the field of testing the quality of fish from aquaculture, a study on the precision of fatty acid (FA) analyses in fish meat and fish feed was undertaken. Different methods were performed in laboratories. In situ transesterification method and extraction of lipids from the fish were followed by capillary gas chromatography with flame ionization detection. The reproducibility (R) values of the majority of FAs were less than 3% of their absolute values. Differences in calculating ionization detector response factors and/or autoxidation caused by faulty sample-handling could lead to variation in quantification of FAs in fish, especially for FA C22:6n-3. Statistical analysis showed a significant correlation between the two laboratories' quantifications of FAs in fish and fish feed (Pearson's correlation coefficient; r = 0.987, r = 0.994, and r = 0.997; for fish Z [trout], fish Š [rainbow trout], and fish feed, respectively). Overall, adequate accuracy was obtained in this study. The proposed method provides a fast and efficient means of identifying fish and feed for quality control purposes.

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“…Since 2007 NIST has developed 10 additional CRMs related to dietary supplement matrices that have values assigned for fatty acids including saw palmetto [68], botanical oils [69], and fish oils [69]. These CRMs are summarized in Table 8 with information on the number of values assigned for fatty acids.…”

Section: Crms For Cholesterol and Fatty Acidsmentioning

confidence: 99%

“…These CRMs are summarized in Table 8 with information on the number of values assigned for fatty acids. The specific nutritional interest in omega-3 and omega-6 fatty acids, often denoted as essential fatty acids, was the motivation for the development of SRM 3274 botanical oils containing omega-3 and omega-6 fatty acids [69]. SRM 3274 consists of four botanical oils (borage, evening primrose, flax, and perilla), which have different profiles of the content of various fatty acids, and in particular, differing levels of α-linolenic acid (an omega-3) and linoleic and γ -linolenic acids (both omega-6) as shown in Fig.…”

Section: Crms For Cholesterol and Fatty Acidsmentioning

confidence: 99%

Evolution of reference materials for the determination of organic nutrients in food and dietary supplements—a critical review

Wise

Phillips

2018

Anal Bioanal Chem

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For over 40 years, food-matrix certified reference materials (CRMs) have been available for determination of trace element content, and a wide variety of materials are available from most producers of CRMs. However, the availability of food-matrix CRMs for organic nutrients has been more limited. The European Commission (EC) Bureau Communautaire de Référence (BCR) and the National Institute of Standards and Technology (NIST) introduced food-matrix CRMs with values assigned for vitamins and other organic nutrients such as fatty acids and carotenoids in the 1990s. The number of organic nutrients for which values were assigned has increased significantly in the past decade, and the approach and analytical methods used for assignment of the certified values have also evolved. Recently, dietary supplement-matrix CRMs such as multivitamin tablets with values assigned for vitamins and carotenoids, and fish and plant oils with values assigned for fatty acids have appeared. The development, evolution, and improvement of food- and dietary supplement-matrix CRMs for determination of vitamins, carotenoids, and fatty acids are described, with emphasis on CRMs made available in the past 10 years. Recent food and dietary supplement CRMs for the determination of organic nutrients include infant formula, multivitamin tablets, milk and egg powders, breakfast cereal, meat homogenate, blueberries, soy flour, fish and plant oils, dry cat food, and protein drink powder. Many of these food- and supplement-matrix CRMs have values assigned for over 80 organic and inorganic nutrients, toxic elements, proximates, and contaminants. The review provides a critical assessment of the challenges and evolving improvements in the production and the analytical methods used for value assignment of these CRMs. The current status and future needs for additional food- and dietary supplement-matrix CRMs for organic nutrients are also discussed.

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Development of botanical and fish oil standard reference materials for fatty acids

Cited by 17 publications

References 16 publications

Orthogonal analytical methods for botanical standardization: Determination of green tea catechins by qNMR and LC–MS/MS

Orthogonal analytical methods for botanical standardization: Determination of green tea catechins by qNMR and LC–MS/MS

Determination of the fatty acids in fish tissue and feed — comparison of different methods and statistical evaluation

Evolution of reference materials for the determination of organic nutrients in food and dietary supplements—a critical review

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