2024
DOI: 10.1242/dev.202838
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Development of functional spermatozoa in mammalian spermiogenesis

Haruhiko Miyata,
Keisuke Shimada,
Yuki Kaneda
et al.

Abstract: Infertility is a global health problem affecting one in six couples, with 50% of cases attributed to male infertility. Spermatozoa are male gametes, specialized cells that can be divided into two parts: the head and the flagellum. The head contains a vesicle called the acrosome that undergoes exocytosis and the flagellum is a motility apparatus that propels the spermatozoa forward and can be divided into two components, axonemes and accessory structures. For spermatozoa to fertilize oocytes, the acrosome and f… Show more

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