2024
DOI: 10.1007/s00216-024-05675-1
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Development of gene-in-plasmid DNA reference materials certified by single-molecule counting

Da-Hye Lee,
Hee-Bong Yoo,
Kee-Suk Hong
et al.

Abstract: The mole, the SI unit for measuring the amount of a substance, was redefined as a fixed number of entities. This definition enables straightforward quantification of substances by counting individual entities. Counting proves particularly effective for quantifying large and discrete biological entities such as DNA, proteins, viruses, and cells, which are challenging to quantify via traditional physical or chemical methods. In this study, we detail our approach to develop gene reference materials certified thro… Show more

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