Development of mushrooms for thrombosis prevention by protoplast fusion

Okamura, Tokumitsu; Takeno, Tomomi; Dohi, Mizuho; Yasumasa, Izumi; Hayashi, Tokiko; Toyoda, Mashiho; Noda, Hiroko; Fukuda, Shoko; Horie, Noboru; Ohsugi, Masahiro

doi:10.1016/s1389-1723(00)89099-4

Cited by 21 publications

(14 citation statements)

References 11 publications

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“…No correlation was found between the inhibitory activity and the phylogenetic relationships, with the exception of mitosporic ascomycota. In addition to our results, one of the reported pharmacological activity of extracts obtained from L. sulphureus was the inhibition of thrombin (Okamura et al, 2000). T. felleus has been researched intensively for its antitumour activities.…”

Section: Resultssupporting

confidence: 77%

Screening of wood damaging fungi and macrofungi for inhibitors of pancreatic lipase

Slanc

Doljak

Mlinarič

et al. 2004

Phytotherapy Research

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A total of 120 methanol and dichloromethane extracts, from 60 species of wood-damaging fungi and 50 methanol/water extracts from macrofungi were screened for inhibition of pancreatic lipase using the chromogenic substrate p-nitrophenylpalmitate. Of the extracts screened, those from Laetiporus sulphureus, Tylopilus felleus and Hygrocybe conica exhibited the highest lipase inhibitory activities of 83% +/- 5%, 96% +/- 3% and 97% +/- 5%, respectively.

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Section: Resultssupporting

confidence: 77%

Screening of wood damaging fungi and macrofungi for inhibitors of pancreatic lipase

Slanc

Doljak

Mlinarič

et al. 2004

Phytotherapy Research

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“…It reduces hyperglycemia in mice with noninsulin dependent diabetes mellitus and acts as an insulin sensitizer in glucose tolerance tests. 12 Okamura et al (2000) screened higher Basidiomycetes for anti-thrombin activity where L. sulphureus was chosen as one of the most active member. To avoid cultivation of the fungus, they used protoplast fusion between L. sulphureus and Hypsizygus marmoreaus, a commonly cultivated Basidiomycete.…”

Section: Anti-ulcermentioning

confidence: 99%

Laetiporus sulphureus (Bull.: Fr.) Murr. as Food as Medicine

Khatua

Ghosh²,

Acharya

2017

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“…Thrombin time (TT) was more over 44-fold longer than in the control group (TT exceeded 600 seconds). They may be a component of the diet in heart disease prevention [Okamura et al 2000].…”

Section: Other Pharmacological Effectsmentioning

confidence: 99%

Laetiporus sulphureus – CHEMICAL COMPOSITION AND MEDICINAL VALUE

Sułkowska-Ziaja

Muszyńska

Gawalska

et al. 2018

Acta Sci.Pol.Hortorum Cultus

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The higher fungi are a rich source of chemical compounds with multi-directional therapeutic and pro-health effects. This review summarizes the results of the most important chemical and biological studies of the fruiting bodies and the mycelial cultures of Laetiporus sulphureus. Numerous studies have demonstrated the antimicrobial, anticancer, cytotoxic, hypoglycemic anti-inflammatory and antioxidant activity of the extracts. Currently, only a few wood-decay fungi have practical use in medicine. Therefore it seems important to continue research on the effectiveness and safety of extracts and compounds of natural origin, including fungi, whose potential is not still used.

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Development of mushrooms for thrombosis prevention by protoplast fusion

Cited by 21 publications

References 11 publications

Screening of wood damaging fungi and macrofungi for inhibitors of pancreatic lipase

Screening of wood damaging fungi and macrofungi for inhibitors of pancreatic lipase

Laetiporus sulphureus (Bull.: Fr.) Murr. as Food as Medicine

Laetiporus sulphureus – CHEMICAL COMPOSITION AND MEDICINAL VALUE

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