Development of paper-based 3D cell culture devices and real-time biosensing applications
Naricha Pupinyo
Abstract:Due to its micro fibrous pores, paper has gained traction in the use as a scaffold for 3D cell culture.�To study melanoma mechanism, screening the amount of melanin production and invasion study are major keys for drug development. In this work, we developed paper-based devices for culturing melanoma cells. Through the development process, we obtained the optimal parameters, which were applied for 3 different projects; 1) Anti-melanogenic effect screening, 2) Impedance-based E-screen assay, and 3) A membrane i… Show more
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